ID A0A374AQ63_9FIRM Unreviewed; 652 AA.
AC A0A374AQ63;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 05-FEB-2025, entry version 16.
DE RecName: Full=Fructose-1,6-bisphosphatase class 3 {ECO:0000256|HAMAP-Rule:MF_01854};
DE Short=FBPase class 3 {ECO:0000256|HAMAP-Rule:MF_01854};
DE EC=3.1.3.11 {ECO:0000256|HAMAP-Rule:MF_01854};
DE AltName: Full=D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 {ECO:0000256|HAMAP-Rule:MF_01854};
GN Name=fbp {ECO:0000256|HAMAP-Rule:MF_01854};
GN ORFNames=DWV72_04985 {ECO:0000313|EMBL:RGH24174.1};
OS Firmicutes bacterium AF12-30.
OC Bacteria; Bacillati; Bacillota.
OX NCBI_TaxID=2292884 {ECO:0000313|EMBL:RGH24174.1, ECO:0000313|Proteomes:UP000262638};
RN [1] {ECO:0000313|EMBL:RGH24174.1, ECO:0000313|Proteomes:UP000262638}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF12-30 {ECO:0000313|EMBL:RGH24174.1,
RC ECO:0000313|Proteomes:UP000262638};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-
CC phosphate + phosphate; Xref=Rhea:RHEA:11064, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:32966, ChEBI:CHEBI:43474, ChEBI:CHEBI:57634; EC=3.1.3.11;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01854};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01854};
CC -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC {ECO:0000256|HAMAP-Rule:MF_01854}.
CC -!- SIMILARITY: Belongs to the FBPase class 3 family. {ECO:0000256|HAMAP-
CC Rule:MF_01854}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RGH24174.1}.
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DR EMBL; QTXP01000006; RGH24174.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A374AQ63; -.
DR UniPathway; UPA00138; -.
DR Proteomes; UP000262638; Unassembled WGS sequence.
DR GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniRule.
DR Gene3D; 3.60.21.10; -; 1.
DR HAMAP; MF_01854; FBPase_class3; 1.
DR InterPro; IPR009164; FBPtase_class3.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR Pfam; PF06874; FBPase_2; 1.
DR PIRSF; PIRSF000906; FBPtase_Bacill; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277, ECO:0000256|HAMAP-
KW Rule:MF_01854}; Hydrolase {ECO:0000256|HAMAP-Rule:MF_01854};
KW Manganese {ECO:0000256|ARBA:ARBA00023211, ECO:0000256|HAMAP-Rule:MF_01854};
KW Reference proteome {ECO:0000313|Proteomes:UP000262638}.
SQ SEQUENCE 652 AA; 75595 MW; B7C217E7CB9B9094 CRC64;
MDQMKYLKEL AVRYPNVAAA STEIINLQAI LHLPKGTEHY LSDVHGEYEK FSHIIRNGSG
AVRSKIEDEF GNTLTKKQKK NLASVIYYPE QKMDLMEEEL PRNELLEWQH DTMVRLVHVA
RAVGNKYTRS KVRKAMNPQF AYIMEELMVE HRRADKKKYV EQILETIITT GRVRQFIAAM
AHLIQDLSID HLHVIGDIYD RGSGPHRIMD CIMKTEKVDI QWGNHDILWM GAASGHRACI
CNVVRICARY NNLDVLENGY GINLIPLARF ALECYKDDDC ELFHASGEVD ESNIREEELN
KKMHKAIAII QFKVEGQLIK RRPDFLMDDR LLLDKVDYEK GTITLDGKEY ELRDKNFPTI
DPEDPYKLTK EEEYVMDHLV TVFKYCAYLQ EHVRFLFAKG NLYKVFNGML LYHGCVPLNE
DGTFREVEIE GRKYAGKELY DILEHLARQG YYEEKNMKAR KYGQDIMWFI WSNENSPVYG
KAKMATFERY FLDDADLKKE KKDYYYQWYE NETVINQILE EFGLDPATGK IVNGHMPVAV
KKGESPIKCG GKLFVIDGGF SKAYQKTTGI AGYTLVSNSY ELKIVAHEPF VSRDTAIREE
TDIHSDTTII NKVTKRKCVL DTDNGKALQE KVADLEQLLW AYQKGLITER IL
//
