ID A0A376CNK1_9CORY Unreviewed; 456 AA.
AC A0A376CNK1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 28-JAN-2026, entry version 19.
DE SubName: Full=Phosphomannomutase/phosphoglucomutase {ECO:0000313|EMBL:STC69842.1};
DE EC=5.4.2.2 {ECO:0000313|EMBL:STC69842.1};
GN Name=manB {ECO:0000313|EMBL:STC69842.1};
GN ORFNames=NCTC11862_01642 {ECO:0000313|EMBL:STC69842.1};
OS Corynebacterium pilosum.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=35756 {ECO:0000313|EMBL:STC69842.1, ECO:0000313|Proteomes:UP000254467};
RN [1] {ECO:0000313|EMBL:STC69842.1, ECO:0000313|Proteomes:UP000254467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC11862 {ECO:0000313|EMBL:STC69842.1,
RC ECO:0000313|Proteomes:UP000254467};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the phosphohexose mutase family.
CC {ECO:0000256|ARBA:ARBA00010231}.
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DR EMBL; UFXQ01000001; STC69842.1; -; Genomic_DNA.
DR RefSeq; WP_018581384.1; NZ_LDYD01000007.1.
DR AlphaFoldDB; A0A376CNK1; -.
DR STRING; 35756.GCA_001044155_02100; -.
DR OrthoDB; 9803322at2; -.
DR Proteomes; UP000254467; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004614; F:phosphoglucomutase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd03089; PMM_PGM; 1.
DR Gene3D; 3.40.120.10; Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3; 3.
DR Gene3D; 3.30.310.50; Alpha-D-phosphohexomutase, C-terminal domain; 1.
DR InterPro; IPR005844; A-D-PHexomutase_a/b/a-I.
DR InterPro; IPR016055; A-D-PHexomutase_a/b/a-I/II/III.
DR InterPro; IPR005845; A-D-PHexomutase_a/b/a-II.
DR InterPro; IPR005846; A-D-PHexomutase_a/b/a-III.
DR InterPro; IPR005843; A-D-PHexomutase_C.
DR InterPro; IPR036900; A-D-PHexomutase_C_sf.
DR InterPro; IPR005841; Alpha-D-phosphohexomutase_SF.
DR NCBIfam; NF007088; PRK09542.1; 1.
DR PANTHER; PTHR43771; PHOSPHOMANNOMUTASE; 1.
DR PANTHER; PTHR43771:SF1; PHOSPHOMANNOMUTASE; 1.
DR Pfam; PF02878; PGM_PMM_I; 1.
DR Pfam; PF02879; PGM_PMM_II; 1.
DR Pfam; PF02880; PGM_PMM_III; 1.
DR Pfam; PF00408; PGM_PMM_IV; 1.
DR PRINTS; PR00509; PGMPMM.
DR SUPFAM; SSF55957; Phosphoglucomutase, C-terminal domain; 1.
DR SUPFAM; SSF53738; Phosphoglucomutase, first 3 domains; 3.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:STC69842.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000254467}.
FT DOMAIN 9..133
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02878"
FT DOMAIN 158..254
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02879"
FT DOMAIN 260..369
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02880"
FT DOMAIN 374..448
FT /note="Alpha-D-phosphohexomutase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00408"
SQ SEQUENCE 456 AA; 48646 MW; 6F363069CA4DBEFF CRC64;
MRSIESVRQV IKAYDVRGVV GEDIDADFVR DTGAAFAHIL RGEGETTIAV GYDMRPSSPE
LVAAFGEGAT SQGLNVLDLG LTSTDELYYA AGTFGCAGAM FTASHNPAKY NGIKLCRAGA
TPVSQDSGLA EITQMLVDEI PAYSGAQGVV EKRNVLDDYA AFLRELVPVD GAGMVVAVDA
ANGMAGLTVP ATLHDFDVRD LYFELDGTFP NHEANPLDPK NLVDLQKFTV EQGAQVGLAF
DGDADRCFVV DELGQPVSPS AITALVAERY LRDAPAGTPI IHNLITSRAV PEIIAENGGT
PVRTRVGHSY IKAEMARTGA LFGGEHSAHY YFTEFFNADS GLLAALHVLA ALSEFDGPLS
QLMAKYERYV ASGELNSTVE DQAAATDAVL DAFASRIDEV DHLDGVTVTL KGTKAWFNVR
ASNTEPLLRL NVEAESQEEV DTLSAEILGV IRSEHP
//
