ID   A0A380KHA3_9STRE        Unreviewed;       239 AA.
AC   A0A380KHA3;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   28-JAN-2026, entry version 16.
DE   SubName: Full=Transglycosylase protein {ECO:0000313|EMBL:SUN63989.1};
DE            EC=3.2.-.- {ECO:0000313|EMBL:SUN63989.1};
GN   Name=isaA_2 {ECO:0000313|EMBL:SUN63989.1};
GN   ORFNames=NCTC12224_02726 {ECO:0000313|EMBL:SUN63989.1};
OS   Streptococcus hyointestinalis.
OC   Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1337 {ECO:0000313|EMBL:SUN63989.1, ECO:0000313|Proteomes:UP000254924};
RN   [1] {ECO:0000313|EMBL:SUN63989.1, ECO:0000313|Proteomes:UP000254924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC12224 {ECO:0000313|EMBL:SUN63989.1,
RC   ECO:0000313|Proteomes:UP000254924};
RG   Pathogen Informatics;
RA   Doyle S.;
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UHFN01000007; SUN63989.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A380KHA3; -.
DR   Proteomes; UP000254924; Unassembled WGS sequence.
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.530.10; -; 1.
DR   InterPro; IPR023346; Lysozyme-like_dom_sf.
DR   InterPro; IPR008258; Transglycosylase_SLT_dom_1.
DR   Pfam; PF01464; SLT; 1.
DR   SUPFAM; SSF53955; Lysozyme-like; 1.
PE   4: Predicted;
KW   Glycosidase {ECO:0000313|EMBL:SUN63989.1};
KW   Hydrolase {ECO:0000313|EMBL:SUN63989.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000254924};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          170..211
FT                   /note="Transglycosylase SLT"
FT                   /evidence="ECO:0000259|Pfam:PF01464"
FT   REGION          80..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        109..118
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   239 AA;  25058 MW;  743FE5F6174404F6 CRC64;
     MTRLKRRYEE RRQAKVRRMT YLLLGGLMVV ASVSVFFFTL AATKVNTETL SAKISSSKAH
     KAIKAKTASS SSQVSALVQV STSTSESSEE TPVETLASTS EEVQDSVDTA TEMTDTTTQQ
     PVAQEATTQV YTDTTTAPVQ TSQAQATTVS TTRLSNGNTA GSVGTTAAAQ MAAATGVPQS
     TWEYIIARES NGNPNAANGS GASGLFQTMP GWGSTATVQD QVNAAIKAYN AQGLSAWGY
//