ID A0A397I7D3_9EURO Unreviewed; 656 AA.
AC A0A397I7D3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 28-JAN-2026, entry version 29.
DE RecName: Full=Fork-head domain-containing protein {ECO:0000259|PROSITE:PS50039};
GN ORFNames=CFD26_100348 {ECO:0000313|EMBL:RLL99336.1};
OS Aspergillus turcosus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=1245748 {ECO:0000313|EMBL:RLL99336.1, ECO:0000313|Proteomes:UP000215289};
RN [1] {ECO:0000313|EMBL:RLL99336.1, ECO:0000313|Proteomes:UP000215289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMR AF 1038 {ECO:0000313|EMBL:RLL99336.1};
RA Parent-Michaud M., Dufresne P.J., Fournier E., Martineau C., Moreira S.,
RA Perkins V., De Repentigny L., Dufresne S.F.;
RT "Draft genome sequences of two Aspergillus turcosus clinical strains
RT isolated from bronchoalveolar lavage fluid: one azole-susceptible and the
RT other azole-resistant.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLL99336.1}.
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DR EMBL; NIDN02000033; RLL99336.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A397I7D3; -.
DR STRING; 1245748.A0A397I7D3; -.
DR OrthoDB; 5954824at2759; -.
DR Proteomes; UP000215289; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:UniProtKB-ARBA.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:UniProtKB-ARBA.
DR CDD; cd00059; FH_FOX; 1.
DR FunFam; 1.10.10.10:FF:000260; Forkhead transcription factor (Sep1); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR050211; FOX_domain-containing.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829:SF343; FORK-HEAD DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Reference proteome {ECO:0000313|Proteomes:UP000215289}.
FT DOMAIN 143..238
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 143..238
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 64..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 240..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 525..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 571..595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 628..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..51
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..79
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..262
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..285
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 534..546
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..656
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 656 AA; 72130 MW; D6D25A2A7FBCA962 CRC64;
MKTPRGLETS LSGRRELGFI PITAPAPPKF TTDSPAKRTP STTYPYATSS SSAMPQSALF
TTFPSANHEK QSSKEKRQLA DSCNDNFADF PEPSFTSKPL KRTLMDAAPL KERTIKKQKR
EDVDLTQLPN PQEMTPIEDD GTKPPYSYAT LIGMSILRAP NRRLTLAQIY KWISDTFSYY
KHSDPGWQNS IRHNLSLNKA FIKQERPKDD PGKGNYWAIE PGMEAQFLKD KPLRRATMSS
LPLPVTSQRE PAQTQSSGTT TWAIPPPNHS LVPKSSRNVD LSSDATIPAS DPALQDDTSD
EGVNAATSQA PLRSSPPQPI HSSPPIAPPR FIRQGTPPTP SHPASSAIVP HSRKRESTTI
NDSGYFSSLE SSAMRPKKTG HILTSDLDID PPRIKRGRAE EEIARIRSSS HDISPRRPGM
LKDAGVVIGS SPVRGEYVSM LPPPLTPVIK FKKPAKPPPS VSPNTNLRNH RKKIQQMVNS
PLKHLGLTDE DLPWSPAFRI QDETYTPSDH LHATFDVFAE SAEEGISTPA YGSPEKRPAK
RARMDSENQT GTVLADITSV SVNSKLGTQA LSSAKSKGPL FPESPSKMPE HGRFGDATHD
DFFSFHLFDE SPVEVDGVDL LQGFQKIGSS SKDESARSKS HTSRPQLNIR SNTALF
//
