ID A0A3B1K8U0_ASTMX Unreviewed; 100 AA.
AC A0A3B1K8U0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 18-JUN-2025, entry version 31.
DE RecName: Full=Cysteine-rich PDZ-binding protein {ECO:0000256|ARBA:ARBA00018615};
DE AltName: Full=Cysteine-rich interactor of PDZ three {ECO:0000256|ARBA:ARBA00032518};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Acestrorhamphidae; Acestrorhamphinae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000050873.1, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000050873.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the CRIPT family.
CC {ECO:0000256|ARBA:ARBA00009021}.
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DR AlphaFoldDB; A0A3B1K8U0; -.
DR FunCoup; A0A3B1K8U0; 790.
DR STRING; 7994.ENSAMXP00000050873; -.
DR Ensembl; ENSAMXT00000033303.1; ENSAMXP00000050873.1; ENSAMXG00000037075.1.
DR GeneTree; ENSGT00950000183100; -.
DR InParanoid; A0A3B1K8U0; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000037075; Expressed in embryo and 14 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030425; C:dendrite; IEA:TreeGrafter.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:TreeGrafter.
DR GO; GO:0030165; F:PDZ domain binding; IEA:TreeGrafter.
DR GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:TreeGrafter.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR InterPro; IPR019367; PDZ-binding_CRIPT.
DR PANTHER; PTHR11805; CYSTEINE-RICH PDZ-BINDING PROTEIN; 1.
DR PANTHER; PTHR11805:SF1; CYSTEINE-RICH PDZ-BINDING PROTEIN; 1.
DR Pfam; PF10235; Cript; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT REGION 15..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 100 AA; 11047 MW; B8B06F5440F6F75C CRC64;
KSKFSEKKLG KVITPDTWKD GARNTTESGG RKLNENKMLT SKKARFDPYG KSGFATCRIC
KSSVHQAGSH YCQGCAYKKG ICAMCGKKVL DTKNYKQTSV
//
