ID A0A3B3BC41_ORYME Unreviewed; 422 AA.
AC A0A3B3BC41;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 18-JUN-2025, entry version 29.
DE SubName: Full=26S proteasome non-ATPase regulatory subunit 11B {ECO:0000313|EMBL:KAF6727191.1};
DE SubName: Full=Proteasome 26S subunit, non-ATPase 11b {ECO:0000313|Ensembl:ENSOMEP00000003166.1};
GN ORFNames=FQA47_011645 {ECO:0000313|EMBL:KAF6727191.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000003166.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000003166.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (DEC-2024) to UniProtKB.
RN [2] {ECO:0000313|EMBL:KAF6727191.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bigg-433 {ECO:0000313|EMBL:KAF6727191.1};
RX PubMed=32938378;
RA Liang P., Saqib H.S.A., Ni X., Shen Y.;
RT "Long-read sequencing and de novo genome assembly of marine medaka (Oryzias
RT melastigma).";
RL BMC Genomics 21:0-0(0).
CC -!- SUBUNIT: Component of the lid subcomplex of the 19S proteasome
CC regulatory particle complex (also named PA700 complex). The 26S
CC proteasome consists of a 20S proteasome core and two 19S regulatory
CC subunits. {ECO:0000256|ARBA:ARBA00062507}.
CC -!- SIMILARITY: Belongs to the proteasome subunit S9 family.
CC {ECO:0000256|ARBA:ARBA00007454}.
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DR EMBL; WKFB01000311; KAF6727191.1; -; Genomic_DNA.
DR STRING; 30732.ENSOMEP00000003166; -.
DR PaxDb; 30732-ENSOMEP00000003166; -.
DR Ensembl; ENSOMET00000011285.1; ENSOMEP00000003166.1; ENSOMEG00000004102.1.
DR GeneTree; ENSGT00530000063301; -.
DR OrthoDB; 1418352at2759; -.
DR Proteomes; UP000261560; Unplaced.
DR Proteomes; UP000646548; Unassembled WGS sequence.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR FunFam; 1.25.40.570:FF:000003; 26S proteasome non-ATPase regulatory subunit 11; 1.
DR Gene3D; 1.25.40.570; -; 1.
DR InterPro; IPR050871; 26S_Proteasome/COP9_Components.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR040780; Rpn6_C_helix.
DR InterPro; IPR040773; Rpn6_N.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10678; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2; 1.
DR Pfam; PF01399; PCI; 1.
DR Pfam; PF18503; RPN6_C_helix; 1.
DR Pfam; PF18055; RPN6_N; 1.
DR SMART; SM00753; PAM; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Proteasome {ECO:0000256|ARBA:ARBA00022942, ECO:0000313|EMBL:KAF6727191.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000646548}.
FT DOMAIN 228..392
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
SQ SEQUENCE 422 AA; 47394 MW; 27FADC2F71FE131E CRC64;
MAAAAVVEFQ RAQSLISTDR DASIDILHSI VRRDVQENDE EAVRVKEQSI LELGTLLAKT
GQAAELGGLL KFVRPFLISI SKAKAARLVR SLLDLFLDME AATGQEVELC LECIEWAKAE
KRTFLRQALE ARLISLYFDT KRYQEALALG SQLLQELKKM DDKALLVEVQ LLESKTYHAL
SNLPKARAAL TSARTTANAI YCPPKLQAAL DMQSGIIHAA EEKDWKTAYS YFFEAFEGYD
SIDSPRAITA LKYMLLCKIV LNLPEEVQAL ISGKLALRYA GRQTDALKCV AQASKNRSLA
DFEKVLTEYK AELRDDPIIN THLAKLYDNL LEQNLIRVIE PFSRVQIEHI SSLIKLSKGD
VERKLSQMIL DKKFHGILDQ GEGVLIIFEE PPVDKTYEAA LETIQNMSKV VDSLYNKAKK
LT
//
