ID A0A3B5XXB1_WHEAT Unreviewed; 225 AA.
AC A0A3B5XXB1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 10-JUN-2026, entry version 30.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN Name=LOC123180859 {ECO:0000313|EnsemblPlants:TraesCS1A02G136400.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS1A02G136400.1, ECO:0000313|Proteomes:UP000019116};
RN [1] {ECO:0000313|EnsemblPlants:TraesCS1A02G136400.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS1A02G136400.1};
RA Rossello M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblPlants:TraesCS1A02G136400.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the SINA (Seven in absentia) family.
CC {ECO:0000256|ARBA:ARBA00009119}.
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DR AlphaFoldDB; A0A3B5XXB1; -.
DR SMR; A0A3B5XXB1; -.
DR EnsemblPlants; TraesCS1A02G136400.1; TraesCS1A02G136400.1; TraesCS1A02G136400.
DR Gramene; TraesCS1A02G136400.1; TraesCS1A02G136400.1; TraesCS1A02G136400.
DR Gramene; TraesCS1A03G0357800.1; TraesCS1A03G0357800.1.CDS; TraesCS1A03G0357800.
DR Gramene; TraesROB_scaffold_079262_01G000100.1; TraesROB_scaffold_079262_01G000100.1; TraesROB_scaffold_079262_01G000100.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000019116; Chromosome 1A.
DR ExpressionAtlas; A0A3B5XXB1; baseline.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR CDD; cd03829; Sina; 1.
DR FunFam; 3.30.40.10:FF:000041; E3 ubiquitin-protein ligase SINAT3; 1.
DR FunFam; 2.60.210.10:FF:000004; E3 ubiquitin-protein ligase SINAT5-like; 1.
DR Gene3D; 2.60.210.10; Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR018121; 7-in-absentia-prot_TRAF-dom.
DR InterPro; IPR052088; E3_ubiquitin-ligase_SINA.
DR InterPro; IPR008974; TRAF-like.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR013010; Znf_SIAH.
DR PANTHER; PTHR10315; E3 UBIQUITIN PROTEIN LIGASE SIAH; 1.
DR PANTHER; PTHR10315:SF145; E3 UBIQUITIN-PROTEIN LIGASE SINAT4; 1.
DR Pfam; PF03145; Sina_TRAF; 1.
DR Pfam; PF21361; Sina_ZnF; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS51081; ZF_SIAH; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00455}.
FT DOMAIN 17..77
FT /note="SIAH-type"
FT /evidence="ECO:0000259|PROSITE:PS51081"
SQ SEQUENCE 225 AA; 25760 MW; 527590D96B26DD47 CRC64;
MDILYVRHAR LGCTTVALRA DKSLATSGCP EIFPYYSKIK HEGQCSFRPY NCPYAGSECA
VAGDIPFLVA HLRDDHKVDM HSGCTFNHRY VKSNPREVEN ATWMLTVFHC FGQYFCLHFE
AFQLGMAPVY MAFLRFMGDE NEARNYTYSL EVGGNGRKMV WEGTPRSIRD SHRKVRDSHD
GLIIQRNMAL FFSGGDRKEL KLRVTGRIWK EQPNLEGTCI PNLCS
//
