ID A0A3D8GMA3_9BACI Unreviewed; 726 AA.
AC A0A3D8GMA3;
DT 16-JAN-2019, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 1.
DT 02-APR-2025, entry version 22.
DE RecName: Full=HD/PDEase domain-containing protein {ECO:0000259|SMART:SM00471};
GN ORFNames=DRW41_18345 {ECO:0000313|EMBL:RDU35417.1};
OS Neobacillus piezotolerans.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC Neobacillus.
OX NCBI_TaxID=2259171 {ECO:0000313|EMBL:RDU35417.1, ECO:0000313|Proteomes:UP000257144};
RN [1] {ECO:0000313|EMBL:RDU35417.1, ECO:0000313|Proteomes:UP000257144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YLB-04 {ECO:0000313|EMBL:RDU35417.1,
RC ECO:0000313|Proteomes:UP000257144};
RA Yu L., Tang X.;
RT "Bacillus sp. YLB-04 draft genome sequence.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDU35417.1}.
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DR EMBL; QNQT01000010; RDU35417.1; -; Genomic_DNA.
DR RefSeq; WP_115453481.1; NZ_QNQT01000010.1.
DR AlphaFoldDB; A0A3D8GMA3; -.
DR OrthoDB; 9806952at2; -.
DR Proteomes; UP000257144; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR011624; Metal-dep_PHydrolase_7TM_extra.
DR InterPro; IPR011621; Metal-dep_PHydrolase_7TM_intra.
DR InterPro; IPR052722; PgpH_phosphodiesterase.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR36442; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR PANTHER; PTHR36442:SF1; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR Pfam; PF07698; 7TM-7TMR_HD; 1.
DR Pfam; PF07697; 7TMR-HDED; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000257144};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 509..663
FT /note="HD/PDEase"
FT /evidence="ECO:0000259|SMART:SM00471"
FT REGION 113..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..136
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 726 AA; 80849 MW; 07DC710CB94770DC CRC64;
MDLLRHQFQN IKRLLDITFF RILFFAFIGV ILFLSMYGNV KPDKLKLGLF NIAEKTVVSP
ITVEDKESTE EKRKHELERV QGVYTLKSEY TQNQVDLVAS IFDTAIKVSD EIQEEKKKAA
PEGESSEPAP AATEPPVSDK VKKLKERLTP AVIDDLPEEV FTALVSADKR QLAIAKDLTL
TAVSNEMSKP IPADEVENSK KKVEEELKFS TLGPSMKRAA ILMRRYAVIQ NEFYDPQATE
EARRRTAETV EPVKILEGQV IVEEGELVSH EIYRQLKLAG LLDSQDSKKP LFGLLLLIVI
ILSSIYYYFL ERKIQPDKKQ TDLLLFGIVF SFSILLMKMA SQFQQFGFEG VSSLFPAAMA
GIIIKILVDE RLAWLTAIVQ GICGSIIFNE ETTGALNMSA GIYILCGGLA ATLFLRDHNA
RSKILPAGIF VSVVNISVIF SLLFLRNTQY NGMEYGLIFI FAAVSGIASA VLAIGLLPFL
EASFGILSTM RLIELSNPNH PLLKKILTEA PGTYHHSVMV ANMSEAACEA IGANGLLARV
GCYYHDIGKT KRPLFFIENQ INRDNPHDRL SPGKSAQIII AHASDGAALL KKHHMPKEII
DIAEQHHGTS LIKFFYHKAK QAGNVNEEDF RYPGPKAQTK ETAIIGIADS VEAAVRSMAQ
PTPEQIESLV HSIISDKLQD GQLNECDLTL REIEVVEHTL CETLKGIFHS RIEYPTEMTK
QKVVDA
//
