ID A0A3G2L3G0_9FLAO Unreviewed; 480 AA.
AC A0A3G2L3G0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 02-APR-2025, entry version 21.
DE SubName: Full=Na+ dependent nucleoside transporter {ECO:0000313|EMBL:AYN66817.1};
GN ORFNames=D1013_05240 {ECO:0000313|EMBL:AYN66817.1};
OS Euzebyella marina.
OC Bacteria; Pseudomonadati; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Euzebyella.
OX NCBI_TaxID=1761453 {ECO:0000313|EMBL:AYN66817.1, ECO:0000313|Proteomes:UP000276309};
RN [1] {ECO:0000313|EMBL:AYN66817.1, ECO:0000313|Proteomes:UP000276309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RN62 {ECO:0000313|EMBL:AYN66817.1,
RC ECO:0000313|Proteomes:UP000276309};
RA Xue C.;
RT "The reduced genetic potential of extracellular carbohydrate catabolism in
RT Euzebyella marina RN62, a Flavobacteriia bacterium isolated from the hadal
RT water.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the concentrative nucleoside transporter (CNT)
CC (TC 2.A.41) family. {ECO:0000256|ARBA:ARBA00009033}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP032050; AYN66817.1; -; Genomic_DNA.
DR RefSeq; WP_121847868.1; NZ_CP032050.1.
DR AlphaFoldDB; A0A3G2L3G0; -.
DR KEGG; emar:D1013_05240; -.
DR OrthoDB; 9766455at2; -.
DR Proteomes; UP000276309; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015293; F:symporter activity; IEA:TreeGrafter.
DR InterPro; IPR008276; C_nuclsd_transpt.
DR InterPro; IPR011657; CNT_C_dom.
DR InterPro; IPR002668; CNT_N_dom.
DR InterPro; IPR011642; Gate_dom.
DR PANTHER; PTHR10590; SODIUM/NUCLEOSIDE COTRANSPORTER; 1.
DR PANTHER; PTHR10590:SF4; SOLUTE CARRIER FAMILY 28 MEMBER 3; 1.
DR Pfam; PF07670; Gate; 1.
DR Pfam; PF07662; Nucleos_tra2_C; 1.
DR Pfam; PF01773; Nucleos_tra2_N; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000276309};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..480
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018083037"
FT TRANSMEM 54..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 458..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..132
FT /note="Concentrative nucleoside transporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01773"
FT DOMAIN 144..243
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
FT DOMAIN 256..476
FT /note="Concentrative nucleoside transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07662"
SQ SEQUENCE 480 AA; 50972 MW; C124BEB940717180 CRC64;
MNVRLCIILL ALCTFFPVLA QETPAPSIES TTINDIIQAS AEIVPNQGFS IDSLWRGIMG
MAVLLVIAFF CSANRKAINW KTVGIGLSLQ LLIAIGVLKV SWVQMAFEAV GEVFISILGF
TRAGSKFLFE GLVVDTNTFG YIFAFQVLPT IVFFSALTSL LFYLGVIQKV VRAMAWLLSK
SLGISGPESL SVAGNIFLGQ TEAPLLIKAY LEKMNRSEIL LVMIGGMATV AGAVLAAYIG
FLGGEDEALQ LVFAKHLLAA SVMAAPGAIV ISKMLYPQTE SVNTDVEVST EKIGSNMLDA
IANGTTEGLR LAVNVGAMLL VFVALIAMVN GILEWTGDLT TINGYIAEHT AYDKLSLEAI
LGTIFAPLMW LIGVNSEDTM LMGQLLGIKL AASEFVGYIQ LAELKDLTTG ANLRYNKSVI
MATYMLCGFA NFASIGIQIG GIGSLAPGQR KTLSEFGMRA VLGGSIASLL SATIAGMILG
//
