ID   A0A3M0J7A6_HIRRU        Unreviewed;       605 AA.
AC   A0A3M0J7A6;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   02-APR-2025, entry version 20.
DE   RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};
GN   ORFNames=DUI87_33087 {ECO:0000313|EMBL:RMB90486.1};
OS   Hirundo rustica rustica.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC   Passeriformes; Sylvioidea; Hirundinidae; Hirundo.
OX   NCBI_TaxID=333673 {ECO:0000313|EMBL:RMB90486.1, ECO:0000313|Proteomes:UP000269221};
RN   [1] {ECO:0000313|EMBL:RMB90486.1, ECO:0000313|Proteomes:UP000269221}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Chelidonia {ECO:0000313|EMBL:RMB90486.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:RMB90486.1};
RA   Formenti G., Chiara M., Poveda L., Francoijs K.-J., Bonisoli-Alquati A.,
RA   Canova L., Gianfranceschi L., Horner D.S., Saino N.;
RT   "A high quality draft genome assembly of the barn swallow (H. rustica
RT   rustica).";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU210713}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004477,
CC       ECO:0000256|RuleBase:RU210713}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RMB90486.1}.
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DR   EMBL; QRBI01000249; RMB90486.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3M0J7A6; -.
DR   STRING; 333673.A0A3M0J7A6; -.
DR   OrthoDB; 567788at2759; -.
DR   Proteomes; UP000269221; Unassembled WGS sequence.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043005; C:neuron projection; IEA:TreeGrafter.
DR   GO; GO:0014069; C:postsynaptic density; IEA:TreeGrafter.
DR   GO; GO:0007420; P:brain development; IEA:TreeGrafter.
DR   GO; GO:0071787; P:endoplasmic reticulum tubular network formation; IEA:TreeGrafter.
DR   GO; GO:0030182; P:neuron differentiation; IEA:TreeGrafter.
DR   Gene3D; 1.20.5.2480; -; 1.
DR   InterPro; IPR003388; Reticulon.
DR   InterPro; IPR046964; RTN1-4.
DR   PANTHER; PTHR45799:SF4; RETICULON-3; 1.
DR   PANTHER; PTHR45799; RETICULON-LIKE PROTEIN; 1.
DR   Pfam; PF02453; Reticulon; 1.
DR   PROSITE; PS50845; RETICULON; 1.
PE   4: Predicted;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824,
KW   ECO:0000256|RuleBase:RU210713};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU210713};
KW   Reference proteome {ECO:0000313|Proteomes:UP000269221};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU210713};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU210713}.
FT   TRANSMEM        430..460
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU210713"
FT   TRANSMEM        539..563
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU210713"
FT   DOMAIN          417..605
FT                   /note="Reticulon"
FT                   /evidence="ECO:0000259|PROSITE:PS50845"
FT   REGION          1..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          104..133
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          160..188
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          368..401
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..30
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        165..188
FT                   /note="Gly residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        368..377
FT                   /note="Gly residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   605 AA;  59307 MW;  4274A80A04B17958 CRC64;
     MADSASEFSL VSSTSTSSST SAASSSASST RAPLGGCTGG GSMSLAAAPG GRERGASPGG
     APQSPPESPE SPFEVVPDRA AFDREFGPAL GQIPEGRVCH FPPKPRGVPG VPGVPGVPGR
     GPAAPARPPP GSAAALEEVS RCVREMHSFT SELLSWDLVE RHGDGGAGDG DGGAGDGDSG
     AGDGDGGGNG GLGISNGVTG AGSGVNGIGS GVIGVTGNGN GVTSVGNGVT GVAGSGGIGV
     TSVGNGVIGT GSGGIGVTGN GVTGVIGVTG VTVTGNGVTS VTGNGVTGVT SVGNGVTSTW
     SGVTSVTGNG VTGVTVTGVT VTGVTSVTST WSGVTGVTAI GNGVTGNGVT GVPSIGNGIV
     GVGNAIGDGP SGPGGVPGSV PSGVPGGGIA DADSSGDSDD TVIEEAPGAV PEDVPRVREL
     LFWRDVRKSA VAFGASLVLL LSLATLSAVT VVAHVALALL SVTISLRVYR AVVQALQKSQ
     EGHPFKAYLD LDVTLSPEAF QAHAAVAAQH LNRALQLLVR LFLVEDLVDS LELALTMWLM
     TYVGAVFNGI TLLILADILA FTLPPLYEKY EVQINHYVHL ARRQTKDLMA KIQAKLPGLA
     KKKPE
//