ID A0A3M2RZ98_9HYPO Unreviewed; 450 AA.
AC A0A3M2RZ98;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 05-FEB-2025, entry version 21.
DE RecName: Full=2-dehydropantoate 2-reductase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CDV36_009755 {ECO:0000313|EMBL:RMJ10637.1};
OS Fusarium kuroshium.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium solani species complex.
OX NCBI_TaxID=2010991 {ECO:0000313|EMBL:RMJ10637.1, ECO:0000313|Proteomes:UP000277212};
RN [1] {ECO:0000313|EMBL:RMJ10637.1, ECO:0000313|Proteomes:UP000277212}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCR3666 {ECO:0000313|EMBL:RMJ10637.1};
RA Stajich J.E., Carrillo J., Kijimoto T., Eskalen A., O'Donnell K.,
RA Kasson M.;
RT "Comparative genomic analysis of Ambrosia Fusariam Clade fungi.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ketopantoate reductase family.
CC {ECO:0000256|ARBA:ARBA00007870}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RMJ10637.1}.
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DR EMBL; NKUJ01000196; RMJ10637.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M2RZ98; -.
DR STRING; 2010991.A0A3M2RZ98; -.
DR OrthoDB; 73846at2759; -.
DR Proteomes; UP000277212; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:TreeGrafter.
DR GO; GO:0008677; F:2-dehydropantoate 2-reductase activity; IEA:TreeGrafter.
DR GO; GO:0050661; F:NADP binding; IEA:TreeGrafter.
DR Gene3D; 1.10.1040.10; N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR050838; Ketopantoate_reductase.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR013332; KPR_N.
DR PANTHER; PTHR43765:SF2; 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR PANTHER; PTHR43765; 2-DEHYDROPANTOATE 2-REDUCTASE-RELATED; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
PE 3: Inferred from homology;
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000277212}.
FT DOMAIN 55..226
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 264..401
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 450 AA; 49092 MW; A1B121B2E095C0A6 CRC64;
MYSQRPSWLE AFHNDTSLPP KLFAWKPSNL NCDPNLGTSS SASTSSVSGD SEQRIYVLGI
GNLGRLFANS LAQAPERPPI TLVVHRKELL TQWMEGQGIE LLRSSTLERN KDFDIEWWTE
SRPETGPVSE VAQGGKLKNL IITTKASAAL PQVDRVRGYL DRSSTVAFAQ NGMSKLWPPH
GPAYVNHRFA PGDAPNFLAC VTTHGVTSQG PFRSLHASQA DVTVGSVLPN ESSSGQSAYL
MKQMLQAPHL NARSVSRGEL WILQLEKLVV NAIINPLTAI LNCKNGDLFT EPDGVIAGII
DQLLSEASHV LQLLVAHESS AEITGQLSNQ DETAATQGDT RLVDLSPGSL HERFSQPHLK
EMVYRVGHKV KDNTSSMLQD VRSGRSTEIR DFNGWLVETA AFLDRSLDVA GHAAMVDLVE
EEEGGQTLNV DRLGARLNGS GAGARKKYRN
//
