ID A0A3M8H4F5_9BACI Unreviewed; 438 AA.
AC A0A3M8H4F5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 18-JUN-2025, entry version 33.
DE SubName: Full=Sensor histidine kinase {ECO:0000313|EMBL:RNC97199.1};
GN ORFNames=EC501_16580 {ECO:0000313|EMBL:RNC97199.1};
OS Lysinibacillus halotolerans.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC Lysinibacillus.
OX NCBI_TaxID=1368476 {ECO:0000313|EMBL:RNC97199.1, ECO:0000313|Proteomes:UP000279909};
RN [1] {ECO:0000313|EMBL:RNC97199.1, ECO:0000313|Proteomes:UP000279909}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCCC 1A12703 {ECO:0000313|EMBL:RNC97199.1,
RC ECO:0000313|Proteomes:UP000279909};
RX PubMed=24814335; DOI=10.1099/ijs.0.061465-0;
RA Kong D., Wang Y., Zhao B., Li Y., Song J., Zhai Y., Zhang C., Wang H.,
RA Chen X., Zhao B., Ruan Z.;
RT "Lysinibacillus halotolerans sp. nov., isolated from saline-alkaline
RT soil.";
RL Int. J. Syst. Evol. Microbiol. 64:2593-2598(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNC97199.1}.
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DR EMBL; RHLQ01000061; RNC97199.1; -; Genomic_DNA.
DR RefSeq; WP_122973457.1; NZ_RHLQ01000061.1.
DR AlphaFoldDB; A0A3M8H4F5; -.
DR OrthoDB; 3173688at2; -.
DR Proteomes; UP000279909; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042802; F:identical protein binding; IEA:TreeGrafter.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd18773; PDC1_HK_sensor; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR016120; Sig_transdc_His_kin_SpoOB.
DR InterPro; IPR039506; SPOB_a.
DR PANTHER; PTHR40448; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR40448:SF1; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF14689; SPOB_a; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR SUPFAM; SSF55890; Sporulation response regulatory protein Spo0B; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:RNC97199.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 193..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 245..438
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 438 AA; 49853 MW; 7D6543C766D9DDF5 CRC64;
MKKANIKIIL ALSSLLVLLF TSFSVYTTNV NIRSTVEEAI TNQNLETAKT ISEQFDIETY
KKFLESPEKN EYYWKINNDL SNIRNKIGAL FVYTIQVESP TMMKTMIAGL PADKQKSFQI
GRPTNVPKKQ IKMVYYEEKP FITSMIKDSQ YGTYLTVAAP IIDESDEVLG YVAIDISAEA
INEVKTSVLE NNLVIFIFNA LFIFIMVICF YFIQKWYQKA VLMEVEYTED TYQEEIKTLI
TSVSSLRHDM TNHLQVIHGL LIIGATDKAQ QYVNSLVNEV QLIKSVSVDA SIEHPGLAIL
LQTKKLAANN HQINMAISVD PNPFDRIKST DMIKILSNLI DNAMDATNEL PEELRQIQVR
CEATDCHYIF EIKNTGPKVP ECEEIFKQGF STKHAEKGKT RGQGLFIVKE VVEKYNGNIA
LYSTNEYETI ARVKIPLK
//
