ID A0A3P7Q6Q4_9BILA Unreviewed; 325 AA.
AC A0A3P7Q6Q4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 05-FEB-2025, entry version 12.
DE RecName: Full=SH2 domain-containing protein {ECO:0000259|PROSITE:PS50001};
GN ORFNames=GPUH_LOCUS15563 {ECO:0000313|EMBL:VDN26239.1};
OS Gongylonema pulchrum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Spiruroidea; Gongylonematidae; Gongylonema.
OX NCBI_TaxID=637853 {ECO:0000313|EMBL:VDN26239.1, ECO:0000313|Proteomes:UP000271098};
RN [1] {ECO:0000313|EMBL:VDN26239.1, ECO:0000313|Proteomes:UP000271098}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYRT01082623; VDN26239.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3P7Q6Q4; -.
DR OrthoDB; 3175255at2759; -.
DR Proteomes; UP000271098; Unassembled WGS sequence.
DR GO; GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:TreeGrafter.
DR GO; GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IEA:TreeGrafter.
DR GO; GO:0008286; P:insulin receptor signaling pathway; IEA:TreeGrafter.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:TreeGrafter.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR032498; PI3K_P85_iSH2.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR10155; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10155:SF10; PI3K21B, ISOFORM B; 1.
DR Pfam; PF16454; PI3K_P85_iSH2; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000271098};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW ProRule:PRU00191}.
FT DOMAIN 1..82
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT COILED 165..192
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 325 AA; 37903 MW; 4B7DE739644E868A CRC64;
MFQDCPSGTF CVRNSSNKGD YTLTLKYGER IRLIKIIVLG GNCGFTHDTL KFDSVVSLIH
YYRRNSLEEY NRQLSTVLLY PLRKPNFERT SWIIDGEHSV EHLLCQLRGL QAAYLRVIRR
DDQVSGELDS LREELQKKRH AWAAFTATHA LFLTQMELLE NNRKLLSDQS EIEQLNNNRE
VQQRRLESIR FQQVQMSDQI ETIEKNIKEN EVLHCSLMPK LSKLHRELNT CQFRLCQMNV
SQVAMDKILQ EVSFLADTEP EPLARILLQL TLRWQPDRYL ALDCTKVFHL FLSFLLIANR
CCALTHSVNK TNSGAHKGSW CDHAF
//
