ID A0A3P9N7V2_POERE Unreviewed; 600 AA.
AC A0A3P9N7V2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 28-JAN-2026, entry version 31.
DE RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000005661.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000005661.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000005661.1};
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [3] {ECO:0000313|Ensembl:ENSPREP00000005661.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000005661.1};
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_008414348.1; XM_008416126.2.
DR AlphaFoldDB; A0A3P9N7V2; -.
DR STRING; 8081.ENSPREP00000005661; -.
DR Ensembl; ENSPRET00000005736.1; ENSPREP00000005661.1; ENSPREG00000003933.1.
DR GeneID; 103468805; -.
DR KEGG; pret:103468805; -.
DR CTD; 79755; -.
DR GeneTree; ENSGT00530000063870; -.
DR OMA; PSAYDHY; -.
DR OrthoDB; 8933073at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000003933; Expressed in caudal fin and 1 other cell type or tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:1990841; F:promoter-specific chromatin binding; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0008544; P:epidermis development; IEA:TreeGrafter.
DR InterPro; IPR039363; ZNF750.
DR InterPro; IPR039064; ZNF750_Znf.
DR PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR Pfam; PF15269; zf-C2H2_7; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 5..58
FT /note="Zinc finger protein 750-like zinc finger"
FT /evidence="ECO:0000259|Pfam:PF15269"
FT REGION 60..161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 318..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 542..600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..76
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..105
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..133
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..146
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..332
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 333..343
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..382
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..457
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..494
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 547..557
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 600 AA; 66425 MW; D27EDAD3940E4A09 CRC64;
METDQERKPK RPHYIPRPPG KPFKYQCFQC PFTCNEKSHL FNHMKYNLCQ NSISLVSQKN
GQAPRQSKAV AKAVSVKPKD CTNVPPEVQS LSSEKQGVEE KKDESRDDTE ELDVGCDSPV
SNDNQSVAKP NTLTDRELTE SDEAKALPRP SAFSPVTPNR DGAEALVATV QRREDSPTSN
ISHPSSPWAR TLPFKSFTPL MVPEYPPYLM PERPLYPPYY LSRHIPVNDP NVPSFQPEFI
DTQRSLVQPP IAPPHGTPFP TYPYRYCHTL HSGPPLPYTL YRPHELSIPI TGHRYFSLDG
YGQGFGQKDY DLYMYSHSSH NSSHSSAQGE SHQSGDKTTR LSPKEGCSAL GSPDRPSQAN
IVLRDSESSQ CMTTGESETS LQLGHASKVV EPVTKDSRQE ESAETLLQLG SHRLDGGSNG
SGLHVSFSDK NHQEESDNVV PLNLSKRDQN HEEKSEQRTM GCDSDNVNGT ELPLNLSLRA
SHSSPSYSSA PSPSEDLPPT VDQDLDEEPC DQRQSAALAL CQLATASSVA SSGDFHIKVQ
SCEDSIDSTT PDSPKNTKST KRAKESGLKR RNNSQSESKS HKLSKKTKET GPTLRRRTRS
//
