ID A0A3P9QEM8_POERE Unreviewed; 1195 AA.
AC A0A3P9QEM8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 28-JAN-2026, entry version 31.
DE SubName: Full=Collagen alpha-1(XVIII) chain-like {ECO:0000313|Ensembl:ENSPREP00000032611.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000032611.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000032611.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000032611.1};
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [3] {ECO:0000313|Ensembl:ENSPREP00000032611.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000032611.1};
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
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DR AlphaFoldDB; A0A3P9QEM8; -.
DR Ensembl; ENSPRET00000032980.1; ENSPREP00000032611.1; ENSPREG00000022058.1.
DR GeneTree; ENSGT00940000164061; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000022058; Expressed in caudal fin and 1 other cell type or tissue.
DR GO; GO:0005594; C:collagen type IX trimer; IEA:TreeGrafter.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IEA:TreeGrafter.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:TreeGrafter.
DR FunFam; 2.60.120.200:FF:000039; Collagen XV alpha 1 chain; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050149; Collagen_superfamily.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR048287; TSPN-like_N.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF372; COLLAGEN ALPHA-1(XVI) CHAIN; 1.
DR Pfam; PF01391; Collagen; 4.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR SMART; SM00210; TSPN; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1195
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017942691"
FT DOMAIN 34..223
FT /note="Thrombospondin-like N-terminal"
FT /evidence="ECO:0000259|SMART:SM00210"
FT REGION 222..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 733..791
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 855..910
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..252
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..265
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..299
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..348
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..382
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 384..394
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..423
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..456
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 458..471
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..545
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 572..584
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..639
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..655
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 736..745
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 757..769
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 780..791
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 881..891
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1195 AA; 121662 MW; F29729178C6B1CE3 CRC64;
MASRIPPWFF GLSLLCCHHS SAYQLLDDRG SHSSLDLTEL IGVPLPPSVS FVTGFEGYPA
YSFGPGANVG RLTKSFIPDP FHHDFAITVM AKPTTRRGGV LFAITDAYQK VVQLGVALSE
VEDGAQNVIL YYTDPETRGG TREAASFKMG EVTGRWARFT LTVQGAEIRL YMDCEEYHRV
AFTRSAQPLT FQTSSGIFVG NAGGTGLPRF VGSIQKLLLN SDPTAPDDQC EEDDPYASGF
GSGDEDYDDS KEGDEVKKIV EEREYPMVFP DPTYGGPVQA PPTEPSLIDD EEGDDEESSG
QEMEMTTVRA ATSRANASER RADASLQVST GQKGEPGEPG PPGSPGPPGQ AVGGGGDPGP
RGPAGPTGLP GKDGEPGMKG ERGLPGAAGF PGLPGDSGPK GEKGDPGLGV PGPPGPPGAP
GPPSKAVMEG SGFEDFDSDT EVVRGPPGPP GPPGLPGLPG SSASGVAPGP AGKDGANGEP
GLAGVDGKDG DPGPAGEKGA KGEPGASGPP GPKGDQGPAG FPGLPGSPGA EGQPGPRGPP
GPPGPSGSRF ATTLEDLEGS GLLEDFGGSP GPQGPPGVPG PPGPKGADGS DGNPGKPGQK
GEQGVSGPPG LPGLDGMKGE KGANGNKGDP GIKGERGRDG VGVPGPPGRP GPPGPVINLQ
DLLLNATDGA FNFSGVFQTQ VPAGPKGDVG LQGLQGPPGI KGEKGEPGFL TGPDGSLMSD
LAGALGTKGI KGDDGVPGAP GVSGPVGPPG PKGEIGFPGR QGRPGLLGPK GEKGDLHGLP
GPPGPPGPPG KPGMFNCPKG LHPNGTVASG NCHQGAKGEK GERGLPGLPA PQSSFLPTGG
WLTKGDQGMK GEKGEAGFPG QPGIPGRSGL VGPKGESVLG PPGPPGMPGP PGAAGYGRPG
AVGPPGPPGP PGLPLRYGSA VAIAGPPGPP GPPGAPGTSS NSAFLKTFST RESMMQQTSR
DEEGTLAYVK ATGNLFLKVP QGWKQIQLGS LIYLSNNIIP QDEPRVAYQV RGETMQRVRS
VKERLNLVAL NQPHSGNMMG LDMADRMCYE QAKAMGLAPN YRAFISSHKQ DLVHVVYPGF
RDSLPVTNLR GDVMFRNWQS IFIGNGGPVN PRIPIYSFDG RDVLADPFWP KKSIWHGSTS
RGLRVIDKHC ETWQADDFSV MGQSSSLTSG LLLGQQTRSC STEFIVLCIE TYKNS
//
