ID   A0A3Q0CWW0_MESAU        Unreviewed;      1040 AA.
AC   A0A3Q0CWW0;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   18-JUN-2025, entry version 25.
DE   SubName: Full=Ataxin-2-like protein isoform X13 {ECO:0000313|RefSeq:XP_021084714.1};
GN   Name=Atxn2l {ECO:0000313|RefSeq:XP_021084714.1};
OS   Mesocricetus auratus (Golden hamster).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Mesocricetus.
OX   NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021084714.1};
RN   [1] {ECO:0000313|RefSeq:XP_021084714.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (MAR-2025) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the ataxin-2 family.
CC       {ECO:0000256|ARBA:ARBA00007503}.
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DR   RefSeq; XP_021084714.1; XM_021229055.1.
DR   AlphaFoldDB; A0A3Q0CWW0; -.
DR   GeneID; 101843643; -.
DR   Proteomes; UP000189706; Unplaced.
DR   GO; GO:0010494; C:cytoplasmic stress granule; IEA:TreeGrafter.
DR   GO; GO:0003729; F:mRNA binding; IEA:TreeGrafter.
DR   GO; GO:0034063; P:stress granule assembly; IEA:TreeGrafter.
DR   InterPro; IPR045117; ATXN2-like.
DR   InterPro; IPR009604; LsmAD_domain.
DR   InterPro; IPR009818; PAM2_motif.
DR   InterPro; IPR047575; Sm.
DR   InterPro; IPR025852; SM_dom_ATX.
DR   PANTHER; PTHR12854; ATAXIN 2-RELATED; 1.
DR   PANTHER; PTHR12854:SF8; ATAXIN-2-LIKE PROTEIN; 1.
DR   Pfam; PF06741; LsmAD; 1.
DR   Pfam; PF07145; PAM2; 1.
DR   Pfam; PF14438; SM-ATX; 1.
DR   SMART; SM01272; LsmAD; 1.
DR   PROSITE; PS52002; SM; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000189706}.
FT   DOMAIN          118..195
FT                   /note="Sm"
FT                   /evidence="ECO:0000259|PROSITE:PS52002"
FT   REGION          1..57
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          313..512
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          546..695
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          727..764
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          815..844
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          859..935
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          992..1025
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        43..57
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        313..324
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        326..338
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        446..458
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        467..479
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        500..511
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        566..579
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        673..689
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        755..764
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        869..893
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        926..935
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1040 AA;  109536 MW;  2EA4CCAAE6777581 CRC64;
     MLKPQPPQQT SQPQQPPPTQ QAVARRPPGG TSPPNGGLPG PLPATTAPAG PPAAVSPCLG
     PAAAAGSGLR RGAESILAAP PQHQERPGAV AIGSVRGQST GKGPPQSPVF EGVYNNSRML
     HFLTAVVGST CDVKVKNGTT YEGIFKTLSS KFELAVDAVH RKASEPAGGP RREDIVDTMV
     FKPSDVLLVH FRNVDFNYAT KDKFTDSAIA MNSKVNGEHK EKVLQRWEGG DSNSDDYDLE
     SDMSNGWDPN EMFKFNEENY GVKTTYDSSL SSYTVPLEKD NSEEFRQREL RAAQLAREIE
     SSPQYRLRIA MENDDGRTEE EKHSAVQRQV SGRESPSLVS REGKYIPLPQ RVREGPRGGV
     RCSGSRGGRP GLSSLPPRGP HHLDNSSPGP GAEARGINGG PSRMSPKAQR PLRGAKTLSS
     PNNRPSGEAS VPPTPAVGRM YPPRSPKSAA PAPVSASCPE PPIGSAVVSS ASIPATSSVV
     DPGAGSISPA SPKISLAPTD VKELPTKEPG RTLEAQELAR IAGKVPGLQN EQKRFQLEEL
     RKFGAQFKLQ PSSSPETGLD PFPSRILKEE AKGKEKEVDG LLTSDPMGSP VSSKTESILD
     KEDKAPLAAV GATEGPEQLP PSCPSQTGSP PVGLIKGDDK EDGPVPEQVK KSTLNPNAKE
     FNPTKPLLSV NKSTSTPTSP GPRTHSTPSI PVLTGQSGLY SPQYISYIPQ IHMGPAVQAP
     QMYPYPVSNS VPGQQGKYRG AKGSLPPQRS DQHQPASAPP MMQAAAAAAG PPLVAATPYS
     SYIPYNPQQF PGQPAMMQPM AHYPSQPVFA PMLQSNPRML TSGSHPQAIV SSSTPQYPSA
     EQPTPQALYA TVHQSYPHHA TQLHGHQPQP ATTPTGSQPQ SQHAAPSPVQ HQAGQAPHLG
     SGQPQQNLYH PGALTGTPPS LPPGPSAQSP QSSFPQPAAV YAIHPHQQLP HGFTNMAHVT
     QAHVQTGVTA APPPHPGAPH PPQVMLLHPP QGHGGPPQGA VPPSGVPALS ASTPSPYPYI
     GHPQAPLPPP GELKIVLAAT
//