ID A0A3Q1GA14_9TELE Unreviewed; 577 AA.
AC A0A3Q1GA14;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 28-JAN-2026, entry version 27.
DE RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
OS Acanthochromis polyacanthus (spiny chromis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Acanthochromis.
OX NCBI_TaxID=80966 {ECO:0000313|Ensembl:ENSAPOP00000026893.1, ECO:0000313|Proteomes:UP000257200};
RN [1] {ECO:0000313|Ensembl:ENSAPOP00000026893.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSAPOP00000026893.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A3Q1GA14; -.
DR Ensembl; ENSAPOT00000002586.1; ENSAPOP00000026893.1; ENSAPOG00000011032.1.
DR GeneTree; ENSGT00530000063870; -.
DR Proteomes; UP000257200; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:1990841; F:promoter-specific chromatin binding; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0008544; P:epidermis development; IEA:TreeGrafter.
DR InterPro; IPR039363; ZNF750.
DR InterPro; IPR039064; ZNF750_Znf.
DR PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR Pfam; PF15269; zf-C2H2_7; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000257200};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 5..58
FT /note="Zinc finger protein 750-like zinc finger"
FT /evidence="ECO:0000259|Pfam:PF15269"
FT REGION 84..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 413..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 460..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..106
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..116
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..148
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..350
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..436
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..526
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..577
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 577 AA; 64633 MW; 65F0B27D660E5704 CRC64;
METAQERKPK RPHYIPRPPG KPFKYQCFQC PFTCNEKSHL FNHMKYNLCK NSISLMAQKN
GQTARQIKAV ARVVPAKSKD CTNFLPAVQD DSPEKQRDEE HKADSGEDKE EIDVGCDNEV
IKDSQSVTKS NTAPETENRE SNETKDLPRP SAFSPVTPKN DGAEAFKSSV QQTEDSRAPL
PTFNHPGFPW GPMSSSIPIK LFPPLMVPEY SPYLLPDRPL YPPYYLPGNH HVNEPNSPSF
QQDFLDPQRP MGQQAIAPSH TSPFPPYPYR YCHTIPPGPP LHYNLYRPHE LPMSLTGPRY
LPLDLYGPPL GTKDYDLYMH SRSIHNRPHT STQEESHHEQ SGDKATRLSP KEGCSAMGSP
DRPSQAHIIQ RDTQAPQYTK TDESHKTLLQ LRTQHSFGFN FCFEQDDMED TDDLAPLNLS
TRNQDKEKTQ SDHGLRCSDT VSLKENELPL NLSLRVSHDS DAHISAPSTS DDLHPRSAEE
MDEEPCDQRQ TAALALCQLA IASSAVSSCD FSAADSSSKA STDAASPRSP KKIKQTTRAK
AAGMKRANSS HVESKCHKSN KRVKAAGRAV RRRPRCC
//
