ID A0A3Q1J9V9_ANATE Unreviewed; 544 AA.
AC A0A3Q1J9V9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 08-OCT-2025, entry version 33.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSATEP00000031712.2};
OS Anabas testudineus (Climbing perch) (Anthias testudineus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Anabantiformes; Anabantoidei; Anabantidae; Anabas.
OX NCBI_TaxID=64144 {ECO:0000313|Ensembl:ENSATEP00000031712.2, ECO:0000313|Proteomes:UP000265040};
RN [1] {ECO:0000313|Ensembl:ENSATEP00000031712.2, ECO:0000313|Proteomes:UP000265040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Wellcome Sanger Institute Data Sharing;
RL Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSATEP00000031712.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAY-2025) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_026222589.1; XM_026366804.1.
DR RefSeq; XP_026222595.1; XM_026366810.1.
DR AlphaFoldDB; A0A3Q1J9V9; -.
DR STRING; 64144.ENSATEP00000031712; -.
DR Ensembl; ENSATET00000032179.3; ENSATEP00000031712.2; ENSATEG00000021848.3.
DR Ensembl; ENSATET00000079365.1; ENSATEP00000075203.1; ENSATEG00000021848.3.
DR GeneID; 113166695; -.
DR CTD; 100003691; -.
DR GeneTree; ENSGT00940000164285; -.
DR InParanoid; A0A3Q1J9V9; -.
DR OrthoDB; 8820570at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000265040; Chromosome 13.
DR GO; GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:TreeGrafter.
DR GO; GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IEA:TreeGrafter.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:TreeGrafter.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR FunFam; 3.30.505.10:FF:000028; Suppressor of cytokine signaling 5; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR022252; SOCS4/SOCS5_dom.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR10155; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10155:SF18; SUPPRESSOR OF CYTOKINE SIGNALING 9 ISOFORM X1; 1.
DR Pfam; PF00017; SH2; 1.
DR Pfam; PF12610; SOCS; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR SMART; SM00252; SH2; 1.
DR SMART; SM00253; SOCS; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50001; SH2; 1.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW Growth regulation {ECO:0000256|ARBA:ARBA00022604};
KW Reference proteome {ECO:0000313|Proteomes:UP000265040};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW ProRule:PRU00191};
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 392..487
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT DOMAIN 482..531
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 104..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 346..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..47
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..359
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 544 AA; 60783 MW; 001CC6F4DE976FD1 CRC64;
MSLPKESGNR GKDRERGARP KVRQSRSEER RDAGGGRKGG KEKKKGLASH EPAAERPVSD
GFEYGELLSD LESRDQSSSS LKESWRWQGL EVAASLLGQE RVTTKPGLGT AGSVSDLSAP
SEGDCRGSSS SRTLRQKIQD AMGQCFPIKT HSAAAPPSPP QALSSSTACA SSKRKILLSE
LMLDDCPFPV GSELAQKWYL IKQHTAPITQ PPTLDSAVVC SPPKSAMATV VEDVDDRLRE
RRRISIEQGV EPPPNAEIHT FEVTAQINPL YKHGPKLAHG MNELAGTDRA SVHQQQQLLL
QRQQQHQLLL QSCLDTLDEV VASASASASV HTCDTISDPL VDPEATATNM PSRTTLPQTE
HQKSHDGYRI HTQIDYIHCL VPDLLQITNL PCYWGVMDRY EAETLLEGKP EGTFLLRDSA
QEDYLFSVSF RRYGRSLHAR IEQWNHNFSF DVHDPSVFHA PTVTGLLEHY KDPNSCMFFE
PLLSNPIHRT QPFSLQHICR AVISSCTTYD GINMLPIPNA LKKHLKEYHY KQRVRVRRMD
TWWE
//
