ID A0A3Q4N730_NEOBR Unreviewed; 470 AA.
AC A0A3Q4N730;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 28-JAN-2026, entry version 31.
DE RecName: Full=Coronin {ECO:0000256|RuleBase:RU280818};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000028519.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000028519.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSNBRP00000028519.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat coronin family.
CC {ECO:0000256|RuleBase:RU280818}.
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DR AlphaFoldDB; A0A3Q4N730; -.
DR STRING; 32507.ENSNBRP00000028519; -.
DR Ensembl; ENSNBRT00000029263.1; ENSNBRP00000028519.1; ENSNBRG00000021715.1.
DR GeneTree; ENSGT00940000159031; -.
DR OMA; ILAWHPC; -.
DR Proteomes; UP000261580; Unassembled WGS sequence.
DR Bgee; ENSNBRG00000021715; Expressed in zone of skin and 4 other cell types or tissues.
DR GO; GO:0051015; F:actin filament binding; IEA:TreeGrafter.
DR GO; GO:0007015; P:actin filament organization; IEA:TreeGrafter.
DR GO; GO:0016477; P:cell migration; IEA:TreeGrafter.
DR FunFam; 2.130.10.10:FF:000003; Coronin; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR015505; Coronin.
DR InterPro; IPR015048; DUF1899.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR10856; CORONIN; 1.
DR PANTHER; PTHR10856:SF41; CORONIN; 1.
DR Pfam; PF08953; DUF1899; 1.
DR Pfam; PF00400; WD40; 3.
DR Pfam; PF16300; WD40_4; 1.
DR SMART; SM01166; DUF1899; 1.
DR SMART; SM01167; DUF1900; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU280818};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 2..66
FT /note="DUF1899"
FT /evidence="ECO:0000259|SMART:SM01166"
FT REPEAT 75..117
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 125..167
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 386..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..435
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..463
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 470 AA; 51339 MW; 3B61D19EF840E2CB CRC64;
MSVVRQSKFR HVFAQAWKAE HCIDDVRVSR VTWDSPLCAV NPKFIAVIIE AGGGGAFLVV
PISKSGRIDQ SCPTVCGHAA PVLDIQWSPH DDNVIASASE DCTVKVWQIP DGGLTSPMTD
ATVTLEGHSK RVGLLAWHPT AFNILLTAGC DNVICVWNVG TGELVYQLDD AHPDLIYNVS
WNKDGSAICT VCKDKALRVI DPRRGAVREK VHDGTRPMRA VFLSDGKILT TGFSRMSERQ
LALWDTKDLS EPMVIQEMDT SNGVLLPFYD PDTNMVYLCG KGDCTIRYFE VTDESPYVHF
LSLYSSKEPQ RGAGFLSKRG VDVNKCEIAR FYKLHERKVE PISMTVPRKS DLFQGDLYPD
TASLEPALLA DEWIAGQDAP PLLVSLSGGY TAPPSKHRDT LRSKPKLVSQ DSGTGAVPPS
AGNVAAPTST PTSAAKETEE ETPQPTAATR ETDGNGDRPK REVGQQQVRC
//
