ID A0A3Q8WVE0_9ACTO Unreviewed; 283 AA.
AC A0A3Q8WVE0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 02-APR-2025, entry version 18.
DE SubName: Full=2-dehydropantoate 2-reductase {ECO:0000313|EMBL:AZN30807.1};
GN ORFNames=EJO69_11225 {ECO:0000313|EMBL:AZN30807.1};
OS Flaviflexus salsibiostraticola.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Actinomycetales;
OC Actinomycetaceae; Flaviflexus.
OX NCBI_TaxID=1282737 {ECO:0000313|EMBL:AZN30807.1, ECO:0000313|Proteomes:UP000270021};
RN [1] {ECO:0000313|EMBL:AZN30807.1, ECO:0000313|Proteomes:UP000270021}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 33148 {ECO:0000313|EMBL:AZN30807.1,
RC ECO:0000313|Proteomes:UP000270021};
RA Bae J.-W.;
RT "Complete genome sequence of Flaviflexus salsibiostraticola KCTC 33148.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ketopantoate reductase family.
CC {ECO:0000256|ARBA:ARBA00007870}.
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DR EMBL; CP034438; AZN30807.1; -; Genomic_DNA.
DR RefSeq; WP_126041870.1; NZ_CP034438.1.
DR AlphaFoldDB; A0A3Q8WVE0; -.
DR KEGG; fsl:EJO69_11225; -.
DR OrthoDB; 4186253at2; -.
DR Proteomes; UP000270021; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0008677; F:2-dehydropantoate 2-reductase activity; IEA:TreeGrafter.
DR GO; GO:0050661; F:NADP binding; IEA:TreeGrafter.
DR Gene3D; 1.10.1040.10; N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR050838; Ketopantoate_reductase.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR013332; KPR_N.
DR PANTHER; PTHR43765:SF2; 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR PANTHER; PTHR43765; 2-DEHYDROPANTOATE 2-REDUCTASE-RELATED; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
PE 3: Inferred from homology;
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000270021}.
FT DOMAIN 4..135
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 169..279
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 283 AA; 29441 MW; 2BFEE2C3BA21FDE0 CRC64;
MLSIIGPGGV GGVLAVIAKN SGIDVEVVAR PETAALINER GLELTSVHHG DSLVSVPART
EPSPGSSIIL ATKSYSLPEI TDSVARSRPA EILALFNGVA HVDRVHELPA PRITCGSIKI
VAERIAPGRL IHHSAFTIVD VEEAAADWQV TAMLRRSGVQ VEVGGGEMEV LWRKLRFLAP
MALLTASTGR PLGPALDGGD ALIAEVAAIA SASGLATAPE QIRANLAKVA PDSSSSLARD
VEAGNRTELD ALGHDLIRRA RAAGIPVPAL EAAVNRIEAR MMS
//
