ID A0A3R9NY59_9BACT Unreviewed; 1193 AA.
AC A0A3R9NY59;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 18-JUN-2025, entry version 23.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=EDE15_2056 {ECO:0000313|EMBL:RSL16538.1};
OS Edaphobacter aggregans.
OC Bacteria; Pseudomonadati; Acidobacteriota; Terriglobia; Terriglobales;
OC Acidobacteriaceae; Edaphobacter.
OX NCBI_TaxID=570835 {ECO:0000313|EMBL:RSL16538.1, ECO:0000313|Proteomes:UP000269669};
RN [1] {ECO:0000313|EMBL:RSL16538.1, ECO:0000313|Proteomes:UP000269669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EB153 {ECO:0000313|EMBL:RSL16538.1,
RC ECO:0000313|Proteomes:UP000269669};
RA Deangelis K.;
RT "Sequencing of bacterial isolates from soil warming experiment in Harvard
RT Forest, Massachusetts, USA.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSL16538.1}.
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DR EMBL; RSDW01000001; RSL16538.1; -; Genomic_DNA.
DR RefSeq; WP_185827098.1; NZ_RSDW01000001.1.
DR AlphaFoldDB; A0A3R9NY59; -.
DR Proteomes; UP000269669; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR CDD; cd14014; STKc_PknB_like; 1.
DR FunFam; 1.10.510.10:FF:000021; Serine/threonine protein kinase; 1.
DR Gene3D; 3.40.50.10610; ABC-type transport auxiliary lipoprotein component; 1.
DR Gene3D; 3.30.200.20; Phosphorylase Kinase, domain 1; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 5.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR026000; Apc5_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_rpt.
DR PANTHER; PTHR43289; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED; 1.
DR PANTHER; PTHR43289:SF6; SERINE_THREONINE-PROTEIN KINASE NEKL-3; 1.
DR Pfam; PF12862; ANAPC5; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF13424; TPR_12; 3.
DR Pfam; PF14559; TPR_19; 1.
DR SMART; SM00220; S_TKc; 1.
DR SMART; SM00028; TPR; 10.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS50005; TPR; 5.
DR PROSITE; PS50293; TPR_REGION; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:RSL16538.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000269669};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527,
KW ECO:0000313|EMBL:RSL16538.1};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 70..328
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REPEAT 657..690
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 732..765
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 812..845
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 852..885
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 892..925
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 99
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1193 AA; 131036 MW; F0DA1A6EBCC5B4C8 CRC64;
MRTPLKGESS SAGELSSDAP TLFGAPDAER YKESSQTYGG SRLSQDGPRS YPGTGGQPIL
EVGSVVAHRY EIVALLGEGG MGAVYKAKDL ELNRTIALKT IRHELGGNLA IVERFKQELI
LSTQVTHRNV VRIFDLGESD RMKFITMEYI EGKDLRTIIY ERGKLPPDEV VDIIAQVCRA
LDAAHSVGVI HRDLKPQNIM RDQNGRILVM DFGLARTLEG DGMTMSGALV GTMEYMSPEQ
ALSKSLDQRS DIYSLGLIFY ELLSGESPFR ADTALASLIR RTQERAMPLS QCTSNISGPL
DQIVARCLER EVEFRYQSVT EVLADLELWQ RKGVVSMVTS QATRRQPVLS MWLWEKRWWL
WGAAALALVF GIAGYVGVNS KSASPTSKEL GAAVQGMSLA ILPFRNSSGD ANDAWIGASV
ADMLSTDIGQ SAHLRTVSTD RLHQVLSDLR IGPDTVIDPD TVRRVAQFSN ADIVVSGQYA
RFGDQIVIDA TIRDIKRGQS VAVKAQALAK DLPTAIDSLA DSVRKNLSLS PDVLQELKAQ
SFKPNSTSVE ALRNYNEGLA LMREGKNLDA YKSFQVATKD DPQFALALSR LAEVQSELGF
ESDAEQSSRR ATELASSEDL PLPEKYLITA NHARIIKDNK QAIEAYKNLA ASWPSDVDVQ
YNLGGLYIAT GDYAKARDMF SKILQADPKN IKALWQMGVV EALFFGNPQA ALDSLSKGLN
LATQVDNQEQ KALILLSMGI SYKKLNNPEE ALRNFEESIA INEKIGQKRG VAAALAEVAN
LQAQRGNTDV ALTDFNKALA LLREIGMKKE AGDTLVDIGV VYQDRGEYDQ ALQRYKEALQ
IQRETGDQNY EALCLYNIAD VYLAKSDTDN AFTYYQQALQ LREKLGVSAR ISETLGGLAE
AYTQTGQYDA ALTSLMRGLE LSRQVGDARQ TALLSHQIGL VFEYQGRFGA AVKSMQESTK
TLRDRGEHGS DMAILLNDLA GALARAGRGD ESSKPLDEAE AIAREVKNDA LIAQILNTRG
DVAFYRGDIK SADQFYKSAL ALSAHAKDND TLVLSKLNVA RMAMAQDHPK EALGMLRPLN
SSDTANAYLS LQRAIANAQA EVDTGDYAKA ERDLEQSLVR SEKAGTRLDS ARINYLLGTS
MRLRGTAEKG RSSYYYGETL RLLDAIRADP GAENVLHRAD LKTIYDDARQ WKM
//
