ID A0A3S0JFX6_9BACI Unreviewed; 146 AA.
AC A0A3S0JFX6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 18-JUN-2025, entry version 14.
DE RecName: Full=Hut operon positive regulatory protein {ECO:0000256|ARBA:ARBA00019377, ECO:0000256|HAMAP-Rule:MF_00779};
GN Name=hutP {ECO:0000256|HAMAP-Rule:MF_00779,
GN ECO:0000313|EMBL:RTQ86812.1};
GN ORFNames=EKG35_19770 {ECO:0000313|EMBL:RTQ86812.1};
OS Lysinibacillus telephonicus.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC Lysinibacillus.
OX NCBI_TaxID=1714840 {ECO:0000313|EMBL:RTQ86812.1, ECO:0000313|Proteomes:UP000276349};
RN [1] {ECO:0000313|EMBL:RTQ86812.1, ECO:0000313|Proteomes:UP000276349}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S5H2222 {ECO:0000313|EMBL:RTQ86812.1,
RC ECO:0000313|Proteomes:UP000276349};
RA Yu L.;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Antiterminator that binds to cis-acting regulatory sequences
CC on the mRNA in the presence of histidine, thereby suppressing
CC transcription termination and activating the hut operon for histidine
CC utilization. {ECO:0000256|ARBA:ARBA00002945, ECO:0000256|HAMAP-
CC Rule:MF_00779}.
CC -!- SUBUNIT: Homohexamer. {ECO:0000256|ARBA:ARBA00011643,
CC ECO:0000256|HAMAP-Rule:MF_00779}.
CC -!- SIMILARITY: Belongs to the HutP family. {ECO:0000256|ARBA:ARBA00009992,
CC ECO:0000256|HAMAP-Rule:MF_00779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RTQ86812.1}.
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DR EMBL; RXNR01000110; RTQ86812.1; -; Genomic_DNA.
DR RefSeq; WP_126296273.1; NZ_CP155468.1.
DR AlphaFoldDB; A0A3S0JFX6; -.
DR OrthoDB; 2388985at2; -.
DR Proteomes; UP000276349; Unassembled WGS sequence.
DR GO; GO:0003729; F:mRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006547; P:L-histidine metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0010628; P:positive regulation of gene expression; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1510.10; Hut operon regulatory protein HutP; 1.
DR HAMAP; MF_00779; HutP; 1.
DR InterPro; IPR015111; Regulatory_HutP.
DR InterPro; IPR023552; Regulatory_HutP_bacillales.
DR InterPro; IPR036482; Regulatory_HutP_sf.
DR NCBIfam; NF002838; PRK03065.1; 1.
DR Pfam; PF09021; HutP; 1.
DR SUPFAM; SSF111064; Hut operon positive regulatory protein HutP; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159, ECO:0000256|HAMAP-Rule:MF_00779};
KW Histidine metabolism {ECO:0000256|ARBA:ARBA00022808, ECO:0000256|HAMAP-
KW Rule:MF_00779}; Reference proteome {ECO:0000313|Proteomes:UP000276349};
KW RNA-binding {ECO:0000256|HAMAP-Rule:MF_00779};
KW Transcription {ECO:0000256|HAMAP-Rule:MF_00779};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00779}.
SQ SEQUENCE 146 AA; 15821 MW; D0C12A9A9E392ED0 CRC64;
MALSKDRIGK NAILLLLSDD SSEHLAMLEQ LNWKSCTGKV GSMDEHKVVA AIETAAKKNG
IINPDVYRES HALYHAIIEA LNGITRGQVQ LGSVLRTVGL SFAVLRGNPY ENEQEGDWIA
VSLYGTIGAP VKGFEHETIG LGINHI
//
