ID A0A3S0Y365_CHLFR Unreviewed; 705 AA.
AC A0A3S0Y365;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 18-JUN-2025, entry version 23.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=PCC6912_18540 {ECO:0000313|EMBL:RUR84260.1};
OS Chlorogloeopsis fritschii PCC 6912.
OC Bacteria; Bacillati; Cyanobacteriota; Cyanophyceae; Nostocales;
OC Chlorogloeopsidaceae; Chlorogloeopsis.
OX NCBI_TaxID=211165 {ECO:0000313|EMBL:RUR84260.1, ECO:0000313|Proteomes:UP000268857};
RN [1] {ECO:0000313|EMBL:RUR84260.1, ECO:0000313|Proteomes:UP000268857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 6912 {ECO:0000313|EMBL:RUR84260.1,
RC ECO:0000313|Proteomes:UP000268857};
RX PubMed=30590650;
RA Will S.E., Henke P., Boedeker C., Huang S., Brinkmann H., Rohde M.,
RA Jarek M., Friedl T., Seufert S., Schumacher M., Overmann J.,
RA Neumann-Schaal M., Petersen J.;
RT "Day and night: Metabolic profiles and evolutionary relationships of six
RT axenic non-marine cyanobacteria.";
RL Genome Biol. Evol. 0:0-0(2019).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RUR84260.1}.
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DR EMBL; RSCJ01000005; RUR84260.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S0Y365; -.
DR STRING; 211165.GCA_000317285_00740; -.
DR Proteomes; UP000268857; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P_dom.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43065:SF50; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000268857};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 308..360
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 432..690
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 361..423
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 705 AA; 77502 MW; 77272098A5593540 CRC64;
MLVNQARSEL AVTEINYNIK INQMGFGFRG QSDNAAIIAA AKAHANSQRL DSTLQRQVKQ
ILQNEVKARE IEYATLVGKD LRIIVNANAD RIGEIFNPSN LVGEVLKNPQ QIKTSEIVSR
AELAKEKPPL PVGIEGYDAL IRYTVTPVRN PQTQEVLGAL VSGDIVNDKP PIVHQTVVTL
GGGYSAVYSR QPNGEFALAT AEQDTNTDKQ GQENQGVRYV SLPDTALLSA AVEARGKPVT
QRIAVEGQTY TVAARALLNF AGETVAILVR GTPETALNAL LRQSLLLQGG IAVLALSVDV
LLATLLARAI ARPIGHLQQV TQAFSGGNFQ ARAQVLSADE IGQLAATFNQ MADSIVSTWQ
IEAIAQEQAR LNAQLQQEIA ERTRTEEALQ QSETLLREKN QILEQTLAQL RSTQAQMVQA
EKMSSLGQLV AGVAHEINNP VNFIHGNLTH AHQYTQDLMG LIQLYQQHYL NPPQAIQAEI
EAIELDFLIE DLIKLFKSMQ VGTERIQEIV LSLRNFSRLD EAEFKAVNIH EGIDSTLMIL
GNRLKAKPEH SSIEIIKNYG QLPSVECYPG QLNQVFMNLL TNAIDALEEH NRQRSPQEIK
ANPGTIRIST EMIEADWIAI YIADNGLGMT EEVRSRIFDS FFITKPIGKG TGLGLSISYE
IVTEKHGGKL YCHSTPGQGT EFVIELPVRQ QIHAPHNLMR SVASV
//
