ID A0A401GYB7_9APHY Unreviewed; 745 AA.
AC A0A401GYB7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 02-APR-2025, entry version 22.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS51873};
GN ORFNames=SCP_1004380 {ECO:0000313|EMBL:GBE87191.1};
OS Sparassis crispa.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Sparassidaceae; Sparassis.
OX NCBI_TaxID=139825 {ECO:0000313|EMBL:GBE87191.1, ECO:0000313|Proteomes:UP000287166};
RN [1] {ECO:0000313|EMBL:GBE87191.1, ECO:0000313|Proteomes:UP000287166}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30375506; DOI=10.1038/s41598-018-34415-6;
RA Kiyama R., Furutani Y., Kawaguchi K., Nakanishi T.;
RT "Genome sequence of the cauliflower mushroom Sparassis crispa
RT (Hanabiratake) and its association with beneficial usage.";
RL Sci. Rep. 8:16053-16053(2018).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBE87191.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BFAD01000010; GBE87191.1; -; Genomic_DNA.
DR RefSeq; XP_027618104.1; XM_027762303.1.
DR AlphaFoldDB; A0A401GYB7; -.
DR STRING; 139825.A0A401GYB7; -.
DR GeneID; 38784108; -.
DR InParanoid; A0A401GYB7; -.
DR OrthoDB; 10009520at2759; -.
DR Proteomes; UP000287166; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR CDD; cd20339; BRcat_RBR_RNF216; 1.
DR CDD; cd20353; Rcat_RBR_RNF216; 1.
DR CDD; cd16630; RING-HC_RBR_RNF216; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR InterPro; IPR047545; BRcat_RBR_RNF216.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR051628; LUBAC_E3_Ligases.
DR InterPro; IPR047546; Rcat_RBR_RNF216.
DR InterPro; IPR047544; RING-HC_RBR_RNF216.
DR InterPro; IPR044066; TRIAD_supradom.
DR PANTHER; PTHR22770:SF47; E3 UBIQUITIN-PROTEIN LIGASE RNF216; 1.
DR PANTHER; PTHR22770; UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED; 1.
DR Pfam; PF01485; IBR; 1.
DR SMART; SM00647; IBR; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000287166};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 366..578
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT REGION 1..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 721..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 652..679
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 25..34
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..252
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 721..733
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 734..745
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 745 AA; 82666 MW; 976E04536837B86E CRC64;
MVNNKIIEIV SSTEGSPAPL VPSPRRLRSR KRRAPTAPAA DVIELTDSED EVQHLRHSRS
PPEKKARAKS PVAGPSQLTS HEAEAPLFLP GSDDEAGPSN PSGSSVAGPP KQAVADKPAE
AAPLAVPEAP VLPPMAFAAV EPDPFVPVPA SQPGSLLDAS HDPYDAYIAQ VLEIIPDVLP
EHVRSLVENH FPNYQEKVVE PVLHVLFEDP TYPKADPKGK GKAKRKREDE VDAEEQARAS
AKPKVDYGSK EREQPSGLQY FTLAHEQLAT DFPDIPVSHL RKAFFRNNML YAPTYMYVFE
ERKSGNLPYK RKTIRARGKG KGVERLDADL EKEKEWVKLK LQETVVRRDP EVAEKLNKQE
SEEAGDGIEC GCCFSSYPFD KMIQCPEAHL FCTACMTTYS ETLLGAHDAN IVCMDQSGCK
LPFPESELRR FLTPKLLALY DRVKQRKEIE AAGLENLEEC PFCDYKVVID NPQERLFRCE
NQECGAVTCR ACKKPDHLPK SCKEVEDDKK LDAQHTIEEA MTRALMRNCP KCQKAFVKEM
GCNKMTCPNC HTLSCYVCRK IITGYDHFNN PPPYNGKSDP AKCLLWDSVE QRHSDEVAAA
AKKALEDYKR EHPDVNDEDI KIDIPPPLPA AGPSNVLYQA DGIHIRAVPI GVNQAQELAR
QQRRQAQIMQ QQMAAARLAQ QQAAQAGAVY NVHLNFNGLP VAVPAPVPLL GFAPPPLPLL
PAPPLHAPVP RPARAPRRAR VARRR
//
