ID A0A484F2H9_9EURY Unreviewed; 243 AA.
AC A0A484F2H9;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 02-APR-2025, entry version 15.
DE RecName: Full=glucose-6-phosphate isomerase {ECO:0000256|ARBA:ARBA00011952};
DE EC=5.3.1.9 {ECO:0000256|ARBA:ARBA00011952};
GN ORFNames=C7391_1384 {ECO:0000313|EMBL:TDQ67831.1};
OS Methanimicrococcus blatticola.
OC Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
OC Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanimicrococcus.
OX NCBI_TaxID=91560 {ECO:0000313|EMBL:TDQ67831.1, ECO:0000313|Proteomes:UP000294855};
RN [1] {ECO:0000313|EMBL:TDQ67831.1, ECO:0000313|Proteomes:UP000294855}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13328 {ECO:0000313|EMBL:TDQ67831.1,
RC ECO:0000313|Proteomes:UP000294855};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate;
CC Xref=Rhea:RHEA:11816, ChEBI:CHEBI:57634, ChEBI:CHEBI:58225;
CC EC=5.3.1.9; Evidence={ECO:0000256|ARBA:ARBA00029321};
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 2/4.
CC {ECO:0000256|ARBA:ARBA00004926}.
CC -!- SIMILARITY: Belongs to the archaeal-type GPI family.
CC {ECO:0000256|ARBA:ARBA00006542}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDQ67831.1}.
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DR EMBL; SNYS01000010; TDQ67831.1; -; Genomic_DNA.
DR RefSeq; WP_133517833.1; NZ_JAHDUW010000001.1.
DR AlphaFoldDB; A0A484F2H9; -.
DR OrthoDB; 49661at2157; -.
DR UniPathway; UPA00109; UER00181.
DR Proteomes; UP000294855; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR CDD; cd02218; cupin_PGI; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR010551; G6P_isomerase_prok.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011051; RmlC_Cupin_sf.
DR Pfam; PF06560; GPI; 1.
DR SUPFAM; SSF51182; RmlC-like cupins; 1.
PE 3: Inferred from homology;
KW Gluconeogenesis {ECO:0000256|ARBA:ARBA00022432};
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152};
KW Isomerase {ECO:0000313|EMBL:TDQ67831.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000294855}.
FT DOMAIN 17..183
FT /note="Glucose-6-phosphate isomerase prokaryote"
FT /evidence="ECO:0000259|Pfam:PF06560"
SQ SEQUENCE 243 AA; 27790 MW; DA5182324C1E9CA4 CRC64;
MVTHPDYSKV STAHSTRKIR DMTDVLMDQT WISYPDKILY DMYREVHLSK EELQKMKEAQ
LRYDITVIPP AMLGPEYVKT AGHYHPCPNS CGAEMLSYPE VYQVIRGTAT YLLQKKDLSD
FIIVEAHEGD VVLIPPNYGH VTVNADSEEL VMANWVSDAF GSEYEPVRCK AGLAYYITED
GIAQNGNYDK MPPISYAKPK SYPEIDLYSG VDMYGLVNDL KKLDFLVNPQ NYPDLFKKPF
YEV
//
