ID A0A485NPM2_LYNPA Unreviewed; 189 AA.
AC A0A485NPM2;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 18-JUN-2025, entry version 21.
DE RecName: Full=Apolipoprotein D {ECO:0000256|ARBA:ARBA00019890, ECO:0000256|PIRNR:PIRNR036893};
DE Short=Apo-D {ECO:0000256|PIRNR:PIRNR036893};
GN ORFNames=LYPA_23C018155 {ECO:0000313|EMBL:VFV31972.1};
OS Lynx pardinus (Iberian lynx) (Felis pardina).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Lynx.
OX NCBI_TaxID=191816 {ECO:0000313|EMBL:VFV31972.1, ECO:0000313|Proteomes:UP000386466};
RN [1] {ECO:0000313|EMBL:VFV31972.1, ECO:0000313|Proteomes:UP000386466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Alioto T., Alioto T.;
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|PIRNR:PIRNR036893}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the calycin superfamily. Lipocalin family.
CC {ECO:0000256|ARBA:ARBA00006889, ECO:0000256|PIRNR:PIRNR036893,
CC ECO:0000256|RuleBase:RU003695}.
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DR EMBL; CAAGRJ010016367; VFV31972.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A485NPM2; -.
DR Proteomes; UP000386466; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0015485; F:cholesterol binding; IEA:TreeGrafter.
DR GO; GO:0007420; P:brain development; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:TreeGrafter.
DR GO; GO:0006869; P:lipid transport; IEA:InterPro.
DR GO; GO:0000302; P:response to reactive oxygen species; IEA:TreeGrafter.
DR GO; GO:0042246; P:tissue regeneration; IEA:InterPro.
DR CDD; cd19437; lipocalin_apoD-like; 1.
DR FunFam; 2.40.128.20:FF:000003; Apolipoprotein D; 1.
DR Gene3D; 2.40.128.20; -; 1.
DR InterPro; IPR026222; ApoD_vertbrte.
DR InterPro; IPR002969; ApolipopD.
DR InterPro; IPR012674; Calycin.
DR InterPro; IPR022271; Lipocalin_ApoD.
DR InterPro; IPR022272; Lipocalin_CS.
DR InterPro; IPR000566; Lipocln_cytosolic_FA-bd_dom.
DR PANTHER; PTHR10612; APOLIPOPROTEIN D; 1.
DR PANTHER; PTHR10612:SF34; APOLIPOPROTEIN D; 1.
DR Pfam; PF00061; Lipocalin; 1.
DR PIRSF; PIRSF036893; Lipocalin_ApoD; 1.
DR PRINTS; PR02058; APODVERTBRTE.
DR PRINTS; PR01219; APOLIPOPROTD.
DR PRINTS; PR00179; LIPOCALIN.
DR SUPFAM; SSF50814; Lipocalins; 1.
DR PROSITE; PS00213; LIPOCALIN; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Lipoprotein {ECO:0000313|EMBL:VFV31972.1};
KW Pyrrolidone carboxylic acid {ECO:0000256|ARBA:ARBA00023283};
KW Reference proteome {ECO:0000313|Proteomes:UP000386466};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|PIRNR:PIRNR036893};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|PIRNR:PIRNR036893"
FT CHAIN 21..189
FT /note="Apolipoprotein D"
FT /evidence="ECO:0000256|PIRNR:PIRNR036893"
FT /id="PRO_5019622016"
FT DOMAIN 44..182
FT /note="Lipocalin/cytosolic fatty-acid binding"
FT /evidence="ECO:0000259|Pfam:PF00061"
SQ SEQUENCE 189 AA; 21455 MW; D48356A671C6F694 CRC64;
MMTALLLFSA LASLFSAADG QAFHLGKCPT PPVQENFDVH KYLGRWYEIE KIPVSFEKGS
CIQANYSLME NGNIKVINQE LRPDGTVNQI EGEATQANLT EPAKLGVKFF WLMPSAPYWV
LATDYENYAL VYSCTTIVWL FHMDHVWILG RNPYLPPETV TYLKDILTSN EIDIEKMTIT
DQVNCPEPL
//
