ID A0A485NZ34_LYNPA Unreviewed; 480 AA.
AC A0A485NZ34;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 02-APR-2025, entry version 17.
DE SubName: Full=Regulator of g-protein signaling 11 {ECO:0000313|EMBL:VFV37368.1};
GN ORFNames=LYPA_23C001555 {ECO:0000313|EMBL:VFV37368.1};
OS Lynx pardinus (Iberian lynx) (Felis pardina).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Lynx.
OX NCBI_TaxID=191816 {ECO:0000313|EMBL:VFV37368.1, ECO:0000313|Proteomes:UP000386466};
RN [1] {ECO:0000313|EMBL:VFV37368.1, ECO:0000313|Proteomes:UP000386466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Alioto T., Alioto T.;
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CAAGRJ010024221; VFV37368.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A485NZ34; -.
DR Proteomes; UP000386466; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0043005; C:neuron projection; IEA:TreeGrafter.
DR GO; GO:0005886; C:plasma membrane; IEA:TreeGrafter.
DR GO; GO:0005096; F:GTPase activator activity; IEA:TreeGrafter.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd04450; DEP_RGS7-like; 1.
DR CDD; cd00068; GGL; 1.
DR FunFam; 1.10.167.10:FF:000001; Putative regulator of g-protein signaling 12; 1.
DR FunFam; 1.10.10.10:FF:000329; regulator of G-protein signaling 9 isoform X2; 1.
DR Gene3D; 1.10.1240.60; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR Gene3D; 4.10.260.10; Transducin (heterotrimeric G protein), gamma chain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR015898; G-protein_gamma-like_dom.
DR InterPro; IPR036284; GGL_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR047016; RGS6/7/9/11.
DR InterPro; IPR047017; RGS6/7/9/11_DHEX_sf.
DR InterPro; IPR040759; RGS_DHEX.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45746; LP21163P; 1.
DR PANTHER; PTHR45746:SF3; REGULATOR OF G-PROTEIN SIGNALING 11; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00631; G-gamma; 1.
DR Pfam; PF00615; RGS; 1.
DR Pfam; PF18148; RGS_DHEX; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00049; DEP; 1.
DR SMART; SM01224; G_gamma; 1.
DR SMART; SM00224; GGL; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF48670; Transducin (heterotrimeric G protein), gamma chain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000386466};
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700}.
FT DOMAIN 26..101
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 313..428
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT REGION 195..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..480
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..472
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 480 AA; 54059 MW; 27008D0C498C3817 CRC64;
MAGVRAGAQM PHLSKMERVV VSMQDPDQGV KMRSQRLLIT VIPHMVAGSD LVEWLIQKYC
ISEEEALHLG TLLVQHGYLY PLRDPRCLVL RPDDTPYRFQ TPYFWTSTLW PATELDYAIY
LAKKNIRKPG ALVGHEKEHY GQLHRKINHA WDLVVMQARE QLRAAKQRRK GDRLVMACQE
QTYWLVNRPP PGVPSVLEQG PERSSCTAGQ AQMSPQGLPS NCSPPGPFQT KNIDFYKREM
ELCRKALGRA RVKSSVCLEA YLKFSSQREL HDPIMSGCLP GNPWVTDDDT YWTLNAPSVA
VPTKLRVERW GFSFQELLED PVGRAHFMAF LGTEFSAENL SFWEACEELR HGGQAQVHAM
VDAVYQQFLA PGAARWVNID SRTMERTLEG LHQPHRYVLD DAQLHIYMLM KKDSYPRFLK
SAAYKDLLAE AVIPPEAKKR VFPFTRKLPH SSPSPALLPA ATSGEPAAAA GGPECGEGGA
//
