ID A0A498LKF3_LABRO Unreviewed; 2311 AA.
AC A0A498LKF3;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 28-JAN-2026, entry version 24.
DE SubName: Full=FRAS1-related extracellular matrix 1-like protein {ECO:0000313|EMBL:RXN07496.1};
GN ORFNames=ROHU_011912 {ECO:0000313|EMBL:RXN07496.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN07496.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN07496.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN07496.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN07496.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FRAS1 family.
CC {ECO:0000256|ARBA:ARBA00005529}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN07496.1}.
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DR EMBL; QBIY01013346; RXN07496.1; -; Genomic_DNA.
DR STRING; 84645.A0A498LKF3; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:TreeGrafter.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007154; P:cell communication; IEA:InterPro.
DR FunFam; 3.40.350.10:FF:000005; SPT16 homolog, facilitates chromatin-remodeling subunit; 1.
DR Gene3D; 2.60.40.2030; -; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR InterPro; IPR038081; CalX-like_sf.
DR InterPro; IPR003644; Calx_beta.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_N.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR039005; CSPG_rpt.
DR InterPro; IPR029148; FACT-SPT16_Nlobe.
DR InterPro; IPR045658; FRAS1-rel_N.
DR InterPro; IPR051561; FRAS1_ECM.
DR InterPro; IPR000994; Pept_M24.
DR PANTHER; PTHR45739:SF3; FRAS-RELATED EXTRACELLULAR MATRIX PROTEIN 1B PRECURSOR; 1.
DR PANTHER; PTHR45739; MATRIX PROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF16184; Cadherin_3; 9.
DR Pfam; PF03160; Calx-beta; 1.
DR Pfam; PF14826; FACT-Spt16_Nlob; 1.
DR Pfam; PF19309; Frem_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR SMART; SM00237; Calx_beta; 1.
DR SMART; SM01285; FACT-Spt16_Nlob; 1.
DR SUPFAM; SSF141072; CalX-like; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR PROSITE; PS51854; CSPG; 10.
PE 1: Evidence at protein level;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A498LKF3};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT REPEAT 347..441
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 466..553
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 574..668
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 695..807
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 829..920
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 941..1035
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1077..1173
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1364..1461
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1482..1574
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1595..1685
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT DOMAIN 1734..1834
FT /note="Calx-beta"
FT /evidence="ECO:0000259|SMART:SM00237"
FT DOMAIN 2018..2172
FT /note="FACT complex subunit SPT16 N-terminal lobe"
FT /evidence="ECO:0000259|SMART:SM01285"
SQ SEQUENCE 2311 AA; 257317 MW; BA374874C1EF606A CRC64;
MWPELWTNAT LPLSALVAPP RFSSPGETKS ATKRKAGGSF HVRGIGTSGF VRRKNLWNWS
AHFLFEETTF PRLFQVFSLA LLGSAALLQG LRVGRGQSVF VTAGELQFHT DGTSEACKVE
VVLTEPITQR VGKLTPQVFD CQFFPDEVRY VHNGSPLLEE DTVMLRVYRF TETETFVENV
LLKIHVVEPQ RSLTELGNVP LVVPEFYGLS SAINSSVLSF KTRPDVICTV RLLSSEINVP
MLGQLVVEDP ESMPASEPGP RKGRHTGITC PGNKACDHNT REVEFLKTDC AEFLTSGLKY
QHLSPPSPEI DYIPIRVEFR DQASRAMLET ESIWIPVLIQ GAMQNQPPNA AFMSTFILEV
DQFILTPMTT AALDAKDDET PQAQLIFNVT KPPAEGYITH LDDHTKTAFS FSWQDLNEMK
IAYQPPNSSH TARRNYEVEF QAIDSSSVPS PPILMHISIR TAETNAPRVS WNMGLDLLEG
QSRPITWEHL QVVDNDNIDA VTLIAMDGPI NGHLSVRGGK GFMFKVKDLR EGVVVYHHSD
SDTTRDYIVF RITDGRHSIR HKFPIYILPK DDTPPFLINN VAFEVQEGGT VRVEEYMLMA
SDLDSSDDYI QYQLITFPRA GQLVKKSSPH EPGIPVKSFL QRDLFQGLIY YKHSGEEVFE
DSFDFILSDV HQPPNLSDRH TVVIHVFPVK DQLPEEVSGT VRSITVKETE VVYITQSHLH
FRDTEHSDTD LMYVITHPCF SAGNTRLSDA GRLFYTDSTN SMKKDAMVPV LKSFTQHAVN
HHKVAYMPPI EDIGPEPLFV QFVFSVSDQQ GGALTGLTFN ITVTPVDNQA PEMFTNLLRV
EEGGGSFLME EHLLVQDVDS SEDQLRVHMK THPQHGRLEL QGTTLLEGDS FSLQDIKALR
VRYIHDDSET LKDSIGLTIT DGINSAHGAL LVQILPVNDE PPQLGSDLRA ELSCKEGGQV
QITVEYLSAT DVDSEDTRLT YMLARTPARG VLQRNGVTVD KFSQLDVLNG LIFYLHTGGE
IGPDPVSDTV TLIVSDGEAG TIDGCCQEDA LPPPVPLHGT LPVYDLNITV MPVNNQVPTI
TLGNVFVVDE GASACLCGGV LEATDPDSHP DQLMFHLVTP PQYGFLENTL PSPGFEKSNA
GLRLHLSSGF INYVQSVHQG VEPTADFFTI SVSDGIERSA PVAFYVIINP TNDEIPSLLL
SNFTVMEGGM KDLSPDILNA VDVDIPADTL TMTILVPPAH GTLVNGIYGL EMNRYKNMNP
EVLQRTLAIQ SFTLQELQQG YHYLLVEDGC EDRVPSLVQP PLGAFTVGIQ AYRTDVAGDK
GMKIMYLHDD TETLKDAFTI QLTDGGHTVQ GTACVRIIPV NDEKPWLLKN AGIEVKALEK
RVISSVVLEA GDHDTPNDQL LYILNAGPRF GLLQLRTEAG WTDLSPGQNF TQEDVEMNRL
WYTHITVSGF KGHDRFHFVL SDGENTTPPQ SFFISVQTVQ KGDIALITKP VTLMEGERVI
LTTDILMATD SGSKPDELIY TLSVPPEHGH LHMVQSPGVP VLSFSQMDVA ANRVCYTHDN
SRFADRDSFS FAVTNGVTSR SGTIHFTVEH SDRIPPTLAI NKGLELTEGS VKTISTDDLK
LTDPDTALEN LTYVVIQSPQ YGKLLFKGLP ISKPHFTQLD INNMDLAYHH LNGRAKIDRF
TFQPTDGTNT GAYIKGRFTQ KDLEQKAVRY VIPADMEVTA DSFEFQITDP AGNTMLPEVM
EFRWSRVELS ASCYRVCENA GTLAVQVVRS GNSKDPAYVG IQVEEGTAKV GKDFTHSSAN
LIQFDPGVSV KMWNIYLKDD GLEENHEKFD VILRAPKNAV LGQRNKATVE IVDPRNGRCS
PDELIVEEDE NQHPFQSPPR IPEPEPPLLE EYTPDPRSGI LWENYPPRGD VPYRTHFSHY
SAGGPQDQEA FHSLGQRQLR ILGRNRHRAH LSEVEKRNQE RVWRFHGLIP VRVEEKAPAP
APRVHSELEI TPIWTWPGYS ADAESVETPQ RDSASFTIDS GVQQHKKGED EFGKVDAIVV
SVGVDEEIVY AKSTALQTWL FGYELTDTIM VFCETKIIFL ASKKKVEFLK QVAITKGNEN
ANGIPPITLL VREKNESNKV NFEKMIEAIR GSKEGKAVGV FMKDKFPGEY MKSWSDMITA
EGLEKVDIST VVAYTMAVKE DGELALMKKA AAITSDVFTK FFKERVMEIV DADELNFLGG
VDPSTVEMCY PPIIQSGGNY SLKFSVVSDK NHMHFGAITC AMGIRYKSYC SNLVRTLMVD
PPQEMQDNYN FLLQVEEELL KEMKHGEQTV H
//
