ID A0A4E0QCF5_9EURY Unreviewed; 222 AA.
AC A0A4E0QCF5;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 18-JUN-2025, entry version 21.
DE RecName: Full=DNA repair and recombination protein RadB {ECO:0000256|ARBA:ARBA00018143, ECO:0000256|HAMAP-Rule:MF_00350};
GN Name=radB {ECO:0000256|HAMAP-Rule:MF_00350};
GN ORFNames=CUN85_01975 {ECO:0000313|EMBL:TGC10947.1};
OS Methanolobus halotolerans.
OC Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
OC Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanolobus.
OX NCBI_TaxID=2052935 {ECO:0000313|EMBL:TGC10947.1, ECO:0000313|Proteomes:UP000297295};
RN [1] {ECO:0000313|EMBL:TGC10947.1, ECO:0000313|Proteomes:UP000297295}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SY-01 {ECO:0000313|EMBL:TGC10947.1,
RC ECO:0000313|Proteomes:UP000297295};
RA Shen Y., Huang H.-H., Lai M.-C., Chen S.-C.;
RT "Isolation and Characterization of Methanogenic Archaea from Saline
RT Meromictic Lake at Siberia.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in DNA repair and in homologous recombination. May
CC regulate the cleavage reactions of the branch-structured DNA. Has a
CC very weak ATPase activity that is not stimulated by DNA. Binds DNA but
CC does not promote DNA strands exchange. {ECO:0000256|ARBA:ARBA00024641,
CC ECO:0000256|HAMAP-Rule:MF_00350}.
CC -!- SIMILARITY: Belongs to the eukaryotic RecA-like protein family. RadB
CC subfamily. {ECO:0000256|ARBA:ARBA00006876, ECO:0000256|HAMAP-
CC Rule:MF_00350}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TGC10947.1}.
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DR EMBL; PGGK01000002; TGC10947.1; -; Genomic_DNA.
DR RefSeq; WP_135388478.1; NZ_PGGK01000002.1.
DR AlphaFoldDB; A0A4E0QCF5; -.
DR OrthoDB; 17644at2157; -.
DR Proteomes; UP000297295; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR CDD; cd01394; archRadB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00350; RadB; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR InterPro; IPR011939; DNA_repair_and_recomb_RadB.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR NCBIfam; TIGR02237; recomb_radB; 1.
DR PANTHER; PTHR22942:SF47; DNA REPAIR AND RECOMBINATION PROTEIN RADB; 1.
DR PANTHER; PTHR22942; RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER; 1.
DR Pfam; PF08423; Rad51; 1.
DR PIRSF; PIRSF003336; RadB; 1.
DR PRINTS; PR01874; DNAREPAIRADA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50162; RECA_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_00350};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|HAMAP-
KW Rule:MF_00350};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172, ECO:0000256|HAMAP-
KW Rule:MF_00350};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00350}; Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00350};
KW Reference proteome {ECO:0000313|Proteomes:UP000297295}.
FT DOMAIN 1..161
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
SQ SEQUENCE 222 AA; 24560 MW; 3CA621AB97D5F178 CRC64;
MTKQLSSGSQ SIDKLLEGGF ETGIVTQIFG EAGSGKTNLC MQLAVECVKN GKKVIYIDTE
AISPQRFKQI AGENAKEIAR EIIIFEPGSF EEQYASVKEI EKLISDRIGL IIVDSATAFY
RFELDQEESS IRSRRELANQ IGFLHGVARK HKLAVVITNQ VYSDVVTGTL KPIGGSGIEH
ISKSIIQLEK TGEGTRRAKL WKHRSIPEGK SCEFRVTSEG IR
//
