ID A0A4P8IB15_9FIRM Unreviewed; 335 AA.
AC A0A4P8IB15;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 28-JAN-2026, entry version 19.
DE RecName: Full=phosphoenolpyruvate--glycerone phosphotransferase {ECO:0000256|ARBA:ARBA00012095};
DE EC=2.7.1.121 {ECO:0000256|ARBA:ARBA00012095};
GN ORFNames=AR1Y2_0307 {ECO:0000313|EMBL:QCP33761.1};
OS Anaerostipes rhamnosivorans.
OC Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales;
OC Lachnospiraceae; Anaerostipes.
OX NCBI_TaxID=1229621 {ECO:0000313|EMBL:QCP33761.1, ECO:0000313|Proteomes:UP000298653};
RN [1] {ECO:0000313|EMBL:QCP33761.1, ECO:0000313|Proteomes:UP000298653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1y2 {ECO:0000313|EMBL:QCP33761.1,
RC ECO:0000313|Proteomes:UP000298653};
RA Bui T.P.N., de Vos W.M.;
RT "Complete genome sequencing of Anaerostipes rhamnosivorans.";
RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone
CC phosphate + pyruvate; Xref=Rhea:RHEA:18381, ChEBI:CHEBI:15361,
CC ChEBI:CHEBI:16016, ChEBI:CHEBI:57642, ChEBI:CHEBI:58702;
CC EC=2.7.1.121; Evidence={ECO:0000256|ARBA:ARBA00001113};
CC -!- PATHWAY: Polyol metabolism; glycerol degradation.
CC {ECO:0000256|ARBA:ARBA00004745}.
CC -!- SUBUNIT: Homodimer. The dihydroxyacetone kinase complex is composed of
CC a homodimer of DhaM, a homodimer of DhaK and the subunit DhaL.
CC {ECO:0000256|ARBA:ARBA00046577}.
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DR EMBL; CP040058; QCP33761.1; -; Genomic_DNA.
DR RefSeq; WP_137327392.1; NZ_CP040058.1.
DR AlphaFoldDB; A0A4P8IB15; -.
DR KEGG; arf:AR1Y2_0307; -.
DR OrthoDB; 9806345at2; -.
DR Proteomes; UP000298653; Chromosome.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0004371; F:glycerone kinase activity; IEA:InterPro.
DR GO; GO:0047324; F:phosphoenolpyruvate-glycerone phosphotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:TreeGrafter.
DR FunFam; 3.30.1180.20:FF:000002; Dihydroxyacetone kinase subunit DhaK; 1.
DR FunFam; 3.40.50.10440:FF:000001; Dihydroxyacetone kinase, DhaK subunit; 1.
DR Gene3D; 3.40.50.10440; Dihydroxyacetone kinase, domain 1; 1.
DR Gene3D; 3.30.1180.20; Dihydroxyacetone kinase, domain 2; 1.
DR InterPro; IPR004006; DhaK_dom.
DR InterPro; IPR050861; Dihydroxyacetone_Kinase.
DR PANTHER; PTHR28629; TRIOKINASE/FMN CYCLASE; 1.
DR PANTHER; PTHR28629:SF4; TRIOKINASE_FMN CYCLASE; 1.
DR Pfam; PF02733; Dak1; 1.
DR SUPFAM; SSF82549; DAK1/DegV-like; 1.
DR PROSITE; PS51481; DHAK; 1.
PE 4: Predicted;
KW Glycerol metabolism {ECO:0000256|ARBA:ARBA00022798};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Pyruvate {ECO:0000313|EMBL:QCP33761.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000298653};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:QCP33761.1}.
FT DOMAIN 7..333
FT /note="DhaK"
FT /evidence="ECO:0000259|PROSITE:PS51481"
SQ SEQUENCE 335 AA; 36155 MW; 8F22D8D1FD536C53 CRC64;
MKKIINEPDH YLKEMLEGIY IAHKDMVTCT DDDLQCLVAK HKKEGKVGIA TGGGSGHLPL
FLGYVGEGML DGCCVGDVFQ SPSADQMLAV TKEIDSGAGV LYIYGNYNGD IFNFDMAAEM
ADMEEDIRVE TVLGADDVAS AGPSAPGEKS TRRGVAGIFF VFKCAGAAAD KMMDLDNVKR
IADKANANVR TMGVALTPCV VPRVGKAGFS IGEDEMEIGM GIHGETGIRR GKIEPADQIV
DEMLNQIVAD LPYESGDEVA VLVNGLGATT LDEQYIVTRR IDKVLAEKGI SVHRYYVGEY
ATALEMAGFS ISLLKLDDEL KEMLDTDAKT PFFRQ
//
