ID A0A4Q0SX35_9BACT Unreviewed; 411 AA.
AC A0A4Q0SX35;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 02-APR-2025, entry version 19.
DE SubName: Full=Nucleoside permease NupC {ECO:0000313|EMBL:RXH54982.1};
GN ORFNames=GRAN_4086 {ECO:0000313|EMBL:RXH54982.1};
OS Granulicella sibirica.
OC Bacteria; Pseudomonadati; Acidobacteriota; Terriglobia; Terriglobales;
OC Acidobacteriaceae; Granulicella.
OX NCBI_TaxID=2479048 {ECO:0000313|EMBL:RXH54982.1, ECO:0000313|Proteomes:UP000289437};
RN [1] {ECO:0000313|EMBL:RXH54982.1, ECO:0000313|Proteomes:UP000289437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF10 {ECO:0000313|EMBL:RXH54982.1,
RC ECO:0000313|Proteomes:UP000289437};
RA Mardanov A.V., Ravin N.V., Dedysh S.N.;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000289437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF10 {ECO:0000313|Proteomes:UP000289437};
RA Oshkin I.Y., Kulichevskaya I.S., Rijpstra W.I.C., Sinninghe Damste J.S.,
RA Rakitin A.L., Ravin N.V., Dedysh S.N.;
RT "Granulicella sibirica sp. nov., a psychrotolerant acidobacterium isolated
RT from an organic soil layer in forested tundra, West Siberia.";
RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the concentrative nucleoside transporter (CNT)
CC (TC 2.A.41) family. {ECO:0000256|ARBA:ARBA00009033}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXH54982.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; RDSM01000003; RXH54982.1; -; Genomic_DNA.
DR RefSeq; WP_128914677.1; NZ_RDSM01000003.1.
DR AlphaFoldDB; A0A4Q0SX35; -.
DR OrthoDB; 9766455at2; -.
DR Proteomes; UP000289437; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015293; F:symporter activity; IEA:TreeGrafter.
DR InterPro; IPR008276; C_nuclsd_transpt.
DR InterPro; IPR011657; CNT_C_dom.
DR InterPro; IPR002668; CNT_N_dom.
DR InterPro; IPR011642; Gate_dom.
DR PANTHER; PTHR10590; SODIUM/NUCLEOSIDE COTRANSPORTER; 1.
DR PANTHER; PTHR10590:SF4; SOLUTE CARRIER FAMILY 28 MEMBER 3; 1.
DR Pfam; PF07670; Gate; 1.
DR Pfam; PF07662; Nucleos_tra2_C; 1.
DR Pfam; PF01773; Nucleos_tra2_N; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000289437};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..81
FT /note="Concentrative nucleoside transporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01773"
FT DOMAIN 93..190
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
FT DOMAIN 196..406
FT /note="Concentrative nucleoside transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07662"
SQ SEQUENCE 411 AA; 43238 MW; 6C046648181A74CC CRC64;
MARFTGLLGL ITFLGIAYAC STNRRAIKLR TVAWGLGLQI VFAFLVIKWS YGQVILHNIS
QVITGLLAHS ADGSAMVFGP LGAPGNALAV FAFAVLPTII FVSAFFAILY HLGIMQQIIR
VVAWIMQRTM GTSGAESTNV AASIFMGQTE APLTIRPFLA GATRSELMTI MTSGMAHVSG
GIMAAYISFG INAQDLLSAV IMTAPGTILV AKMLVPETEV PATAGTVKMP PNEEHANENF
IAAIARGTID GGQLAFNVAI MLISFLALVG LLNATLLGIS NMAWAHGIRT PHSLNAILGF
FCAPVAWLIG IPWHEAPAIG NLLGTRAVLN EFVAYTSLGL QKSTLTPRTF SIATFALCGF
ANLGSIGMQI GGIGALVPNR RNDLAALGFR AMLAGTMANL MSASIVSMLI K
//
