ID A0A4Q1BWF4_TREME Unreviewed; 330 AA.
AC A0A4Q1BWF4;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 28-JAN-2026, entry version 19.
DE RecName: Full=DASH complex subunit DAD4 {ECO:0000256|ARBA:ARBA00020259};
DE AltName: Full=Outer kinetochore protein DAD4 {ECO:0000256|ARBA:ARBA00030569};
GN ORFNames=M231_00058 {ECO:0000313|EMBL:RXK42504.1};
OS Tremella mesenterica (Jelly fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Tremellaceae; Tremella.
OX NCBI_TaxID=5217 {ECO:0000313|EMBL:RXK42504.1, ECO:0000313|Proteomes:UP000289152};
RN [1] {ECO:0000313|EMBL:RXK42504.1, ECO:0000313|Proteomes:UP000289152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28783 {ECO:0000313|EMBL:RXK42504.1,
RC ECO:0000313|Proteomes:UP000289152};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore
CC {ECO:0000256|ARBA:ARBA00004629}. Cytoplasm, cytoskeleton, spindle
CC {ECO:0000256|ARBA:ARBA00004186}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DASH complex DAD4 family.
CC {ECO:0000256|ARBA:ARBA00009754}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXK42504.1}.
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DR EMBL; SDIL01000001; RXK42504.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4Q1BWF4; -.
DR STRING; 5217.A0A4Q1BWF4; -.
DR VEuPathDB; FungiDB:TREMEDRAFT_25165; -.
DR InParanoid; A0A4Q1BWF4; -.
DR OrthoDB; 5516652at2759; -.
DR Proteomes; UP000289152; Unassembled WGS sequence.
DR GO; GO:0042729; C:DASH complex; IEA:InterPro.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0072686; C:mitotic spindle; IEA:InterPro.
DR GO; GO:0008608; P:attachment of spindle microtubules to kinetochore; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR InterPro; IPR013959; DASH_Dad4.
DR PANTHER; PTHR28222; DASH COMPLEX SUBUNIT DAD4; 1.
DR PANTHER; PTHR28222:SF1; DASH COMPLEX SUBUNIT DAD4; 1.
DR Pfam; PF08650; DASH_Dad4; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Centromere {ECO:0000256|ARBA:ARBA00023328};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Kinetochore {ECO:0000256|ARBA:ARBA00022838};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000289152}.
FT REGION 84..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..105
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 330 AA; 36918 MW; 6B521D1B7C0A3693 CRC64;
MENPHEAEQA VLLERIIKNV DKCNEAVLEM NHCIKEFLES STSTHVAAQL FANYSRNVNY
NLEALGNMPK PVLKYDISAR KRPGSISNTV ERQTKETEVD SEHSPTKMNY SSNSSSSAED
NTIIHAYSYC QRLPLCHISQ EEASYSPDST WAQENALPLT PISNHEQDEE EGSLEHAREY
DPSNVAVYLD TSDLPEGTDI PQTLEEIEAS KYDSAKGWKL LCPDHVGVDG SRDQLTSGYL
KPKDVFLTSP KCQSCSRRWT EEGIRNTWVT VLYDGGDDSF RWWCGAGPCY SAVDVETDKL
QKDGYAVTWL DELVETLGIE DDFVAGPADG
//
