ID A0A4Q2T3G0_9ACTN Unreviewed; 318 AA.
AC A0A4Q2T3G0;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 02-APR-2025, entry version 28.
DE SubName: Full=Ketopantoate reductase family protein {ECO:0000313|EMBL:RYC12551.1};
GN ORFNames=EUA94_07740 {ECO:0000313|EMBL:RYC12551.1};
OS Nocardioides zhouii.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=1168729 {ECO:0000313|EMBL:RYC12551.1, ECO:0000313|Proteomes:UP000291101};
RN [1] {ECO:0000313|EMBL:RYC12551.1, ECO:0000313|Proteomes:UP000291101}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HLT2-9 {ECO:0000313|EMBL:RYC12551.1,
RC ECO:0000313|Proteomes:UP000291101};
RA Liu Q., X Y.-H.;
RT "Novel species of Nocardioides.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ketopantoate reductase family.
CC {ECO:0000256|ARBA:ARBA00007870}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RYC12551.1}.
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DR EMBL; SDWV01000006; RYC12551.1; -; Genomic_DNA.
DR RefSeq; WP_129426304.1; NZ_SDWV01000006.1.
DR AlphaFoldDB; A0A4Q2T3G0; -.
DR OrthoDB; 9796561at2; -.
DR Proteomes; UP000291101; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0008677; F:2-dehydropantoate 2-reductase activity; IEA:TreeGrafter.
DR GO; GO:0050661; F:NADP binding; IEA:TreeGrafter.
DR Gene3D; 1.10.1040.10; N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR050838; Ketopantoate_reductase.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR013332; KPR_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43765:SF2; 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR PANTHER; PTHR43765; 2-DEHYDROPANTOATE 2-REDUCTASE-RELATED; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000291101}.
FT DOMAIN 4..141
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 180..299
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 318 AA; 32792 MW; CB3D12D283D1B3F9 CRC64;
MDYVVYGTGA VGGVIGGHLH LAGSPVTLVA RGAHLEAIRA GGLVLDAGDG RHRIDAPATD
TAADVAWTDD TVVILAVKSH QAAVALADLR EHAPPGTAIV CATNGIATEA AALRLFARTY
AVCVMLPSTH LEPGVVVAGS HPTPAILDIG RIPGGTDATT AAVSADLHAA RIESVERDDI
MAWKRRKLIM NLGNGVDASF ARGDAADDLA DLAQAEGERV LAAAGATVVT ADEDRERRGS
ILQRRPDLER RGGSTWQSLA RGTGDSEIDY LAGEIVLQGR LHGVPTPVNE AVVAATRALA
YAGGSPRSLD AAEVLARL
//
