ID A0A4Q9G5C6_9RHOB Unreviewed; 673 AA.
AC A0A4Q9G5C6;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 28-JAN-2026, entry version 29.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:TBN43813.1};
GN ORFNames=EYE42_01360 {ECO:0000313|EMBL:TBN43813.1};
OS Paracoccus subflavus.
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Rhodobacterales; Paracoccaceae; Paracoccus.
OX NCBI_TaxID=2528244 {ECO:0000313|EMBL:TBN43813.1, ECO:0000313|Proteomes:UP000293520};
RN [1] {ECO:0000313|EMBL:TBN43813.1, ECO:0000313|Proteomes:UP000293520}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GY0581 {ECO:0000313|EMBL:TBN43813.1,
RC ECO:0000313|Proteomes:UP000293520};
RA Zhang G.;
RT "Paracoccus subflavus sp. nov., isolated from marine sediment of the
RT Pacific Ocean.";
RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TBN43813.1}.
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DR EMBL; SISK01000001; TBN43813.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4Q9G5C6; -.
DR OrthoDB; 9803139at2; -.
DR Proteomes; UP000293520; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004020; F:adenylylsulfate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 3.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR048931; WHD_2nd_SelB_bact.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF21214; WHD_2nd_SelB_bact; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 3.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:TBN43813.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000293520}.
FT DOMAIN 1..168
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 646..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 673 AA; 71735 MW; 2A55BE7928967152 CRC64;
MIVGTAGHID HGKTALVKAL TGTDADRLAE EKARGITIDL GFAYADLGGG SVTGFVDVPG
HERLIHTMLA GAGGIDMALL VVAADDGVMP QTREHMAILD LLGIGRGIVA LTKADLADDA
RRQAVAAEIR ETLADTVLAD APILPVSSLT GEGLDALRAA LIDAETQTVA RRADGPMRLA
VDRSFTLSGA GTVVTGTMLT GRVALGDQVV VSPTGLPARV RAIHAQNRPA AEGVAGQRCA
LNLAGEAISK GAIHRGHVVL SPALHAPTDR IDAWLTVLPG EPKPIGTWFP ARLHSHAVEA
GARIVPLADP IRPGRGGPVQ IVLDRPIAAA VHDRFILRDV SASRTIGGGR FLDLRPPARK
RRSPERLALI GAAQADDPAK ALAAMLTVTS VDLPGFARDR SLSVPAIAAT VAAADAVTIG
DLAIGRDALA RLRDGLTTAL AHFHEDNPDL PGMGRERLRL MLQPRMPKDA FLAFLRTEAD
AGRALPDGAF VRLPGHEVRL TPEDEALWQR IGPALLGEMR FRPPRVRDLA TDFGIDERDV
RRVLKLTQRL GRTDQIAHDH FFARAVTAEM VAIIHDVAAQ AENGWFTAPA FRDRVQNGRK
VAIEILDFFD RHGLTLRRGD LRRINPHRAD LFGDLGRESS PVGRPVFKTG WGSEPVPGGF
DSHSLPPESQ GQE
//
