ID A0A4R1HTT6_PSEEN Unreviewed; 610 AA.
AC A0A4R1HTT6;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 28-JAN-2026, entry version 24.
DE SubName: Full=Selenocysteine-specific elongation factor {ECO:0000313|EMBL:TCK26087.1};
GN ORFNames=EV378_1915 {ECO:0000313|EMBL:TCK26087.1};
OS Pseudonocardia endophytica.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Pseudonocardia.
OX NCBI_TaxID=401976 {ECO:0000313|EMBL:TCK26087.1, ECO:0000313|Proteomes:UP000295560};
RN [1] {ECO:0000313|EMBL:TCK26087.1, ECO:0000313|Proteomes:UP000295560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44969 {ECO:0000313|EMBL:TCK26087.1,
RC ECO:0000313|Proteomes:UP000295560};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TCK26087.1}.
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DR EMBL; SMFZ01000001; TCK26087.1; -; Genomic_DNA.
DR RefSeq; WP_132422791.1; NZ_SMFZ01000001.1.
DR AlphaFoldDB; A0A4R1HTT6; -.
DR OrthoDB; 9803139at2; -.
DR Proteomes; UP000295560; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:TCK26087.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000313|EMBL:TCK26087.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000295560}.
FT DOMAIN 1..169
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 610 AA; 63324 MW; 55CCD0AB6619B984 CRC64;
MHVVCTAGHV DHGKSTLVRT LTGMEPDRFA EERRRGMTID LGFAWTTLPG GDTVAFVDVP
GHERFVSTML AGAGPVPAAL FVVAADEGWM PQSAEHADAL EAIGVSRGLL VVTRSDLLDP
ELAGEDARAE LAARGWDWPA VAVSATTGSG IDALRSALEE LVGGLPAPDA GADVRFWVDR
AFTVRGSGTV VTGTLPAGTL RTGDELELDT GDGPLTVGVR ALQALGEPVD EAHPVARVAV
NLRGVPRDRV RRGDVLLSGR WLRAGEIDVR LGGLRGEPAA TDLPTELTLH AGSVAVPVRV
RPLGPDDGGL VRLRLARPLP LRIGDRAVLR DPGGRRVLAG VTVLDVAPPA LRRRGAAARR
ADDLADATGT PDATAELTRR GAVRADDLRA MGIPQPDVDG LAARVPGGAG WLLDPDRAGA
AARDLAAAVA AHDRTDPLDP GLPLAAARRA AGLPDSALVP VVLAASRDAG PRDLVVDGGR
VRSATGGGLP DAVRAAMDAL HAELTDTPFA APDADRLAAL GLGPRELASL ERAGELLRIT
PGTSPEVVLL PDAEDRAVAL LAELDEEFTL SAARQALATT RRVAVPLLER LARNGRTVRT
ASGGHRLRGV
//
