ID   A0A4R3MD36_9HYPH        Unreviewed;       810 AA.
AC   A0A4R3MD36;
DT   31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT   31-JUL-2019, sequence version 1.
DT   08-OCT-2025, entry version 14.
DE   SubName: Full=Soluble lytic murein transglycosylase {ECO:0000313|EMBL:TCT11520.1};
GN   ORFNames=EDC22_104283 {ECO:0000313|EMBL:TCT11520.1};
OS   Tepidamorphus gemmatus.
OC   Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC   Hyphomicrobiales; Tepidamorphaceae; Tepidamorphus.
OX   NCBI_TaxID=747076 {ECO:0000313|EMBL:TCT11520.1, ECO:0000313|Proteomes:UP000295678};
RN   [1] {ECO:0000313|EMBL:TCT11520.1, ECO:0000313|Proteomes:UP000295678}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19345 {ECO:0000313|EMBL:TCT11520.1,
RC   ECO:0000313|Proteomes:UP000295678};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT   most valuable type-strain genomes for metagenomic binning, comparative
RT   biology and taxonomic classification.";
RL   Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transglycosylase Slt family.
CC       {ECO:0000256|ARBA:ARBA00007734}.
CC   -!- SIMILARITY: Belongs to the virb1 family.
CC       {ECO:0000256|ARBA:ARBA00009387}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TCT11520.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; SMAK01000004; TCT11520.1; -; Genomic_DNA.
DR   RefSeq; WP_132806266.1; NZ_SMAK01000004.1.
DR   AlphaFoldDB; A0A4R3MD36; -.
DR   OrthoDB; 9815002at2; -.
DR   Proteomes; UP000295678; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0042597; C:periplasmic space; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0008933; F:peptidoglycan lytic transglycosylase activity; IEA:InterPro.
DR   GO; GO:0000270; P:peptidoglycan metabolic process; IEA:InterPro.
DR   CDD; cd13401; Slt70-like; 1.
DR   Gene3D; 1.10.530.10; -; 1.
DR   Gene3D; 1.25.20.10; Bacterial muramidases; 1.
DR   InterPro; IPR023346; Lysozyme-like_dom_sf.
DR   InterPro; IPR008939; Lytic_TGlycosylase_superhlx_U.
DR   InterPro; IPR000189; Transglyc_AS.
DR   InterPro; IPR008258; Transglycosylase_SLT_dom_1.
DR   PANTHER; PTHR37423:SF2; MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE C; 1.
DR   PANTHER; PTHR37423; SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE-RELATED; 1.
DR   Pfam; PF01464; SLT; 1.
DR   SUPFAM; SSF48435; Bacterial muramidases; 1.
DR   SUPFAM; SSF53955; Lysozyme-like; 1.
DR   PROSITE; PS00922; TRANSGLYCOSYLASE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000295678};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           27..810
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5020657987"
FT   DOMAIN          602..707
FT                   /note="Transglycosylase SLT"
FT                   /evidence="ECO:0000259|Pfam:PF01464"
SQ   SEQUENCE   810 AA;  86653 MW;  2A5047F88E30ED76 CRC64;
     MPIIRLLALS TAIAPLLLSL SLPAAAFVLA KPEGEALATT AAARKSSAQR PVPLPPHRPA
     ELAAANAVSA DGETVADAGT GAAGRGIEQA DTAQAAALAE GLPLPRPRPA DAPSPNRVVG
     AGPIKVVDQP TAAATKEALN HIAAKRFDQA LEIQKRLPDP AAVKLVEFYY VRDAALHAPY
     PRIAAFLAEN HDWPNRDLIQ RRFEVALLAQ RAPTEAILAV FADHSPTTTA GSIALASALA
     SVGETARANE LARTLWRREQ MTEGEERLVA ERFGDALTRD DHKARMDRLL DKGETSGALR
     AARRLGGDEL KLAEARIAVI RRSRSAGTLL DQVPQALRQD PGYILSKAQW YRRLGRYSEA
     ARIIATARID PQKVAGRDEW SLERRIIARE LIELGDPAGA YAIVSQHGAE SAVDRLDSEW
     LAGWIALRFL HDPDRADKHF SALTEIATTP ISLARAQYWL GRSAEARGAS DAALRHYLEA
     GRHSTTYYGQ LALARIGHAS IPELRKPLIA DTAHRIVARR DSMRAMRLLA QIGMEDDAAR
     FMISMAQEAQ DAVTAIGVAE TAYRMGLTSA TVWIGKAAHQ AGYPTEIYAF ATGGIPAYAD
     LGPGVETAVV NAIARQESVF NPAAISPAGA RGLMQLMPAT AQTTARRYGQ PYDVKWLTSD
     PTYNAAVGAA HLGDLTSDFG TAYALVFAAY NAGAARVVDW IKRFGDPRKG DIDPVDWVEL
     IPFSETRNYV QRVLEGVQVY RARLGGTNQL LIAQDLRIPI DMQTSIATAT DGPGSADSGV
     PGVFSSFGGP ELTTGSSTVP ASALGFGGAR
//