ID A0A4R3YUY3_9GAMM Unreviewed; 306 AA.
AC A0A4R3YUY3;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 02-APR-2025, entry version 17.
DE SubName: Full=4-hydroxy-tetrahydrodipicolinate synthase {ECO:0000313|EMBL:TCV95174.1};
GN ORFNames=EDC52_106105 {ECO:0000313|EMBL:TCV95174.1};
OS Biostraticola tofi.
OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC Enterobacterales; Bruguierivoracaceae; Biostraticola.
OX NCBI_TaxID=466109 {ECO:0000313|EMBL:TCV95174.1, ECO:0000313|Proteomes:UP000295719};
RN [1] {ECO:0000313|EMBL:TCV95174.1, ECO:0000313|Proteomes:UP000295719}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19580 {ECO:0000313|EMBL:TCV95174.1,
RC ECO:0000313|Proteomes:UP000295719};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family. {ECO:0000256|ARBA:ARBA00007592,
CC ECO:0000256|PIRNR:PIRNR001365}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TCV95174.1}.
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DR EMBL; SMCR01000006; TCV95174.1; -; Genomic_DNA.
DR RefSeq; WP_131865861.1; NZ_SMCR01000006.1.
DR AlphaFoldDB; A0A4R3YUY3; -.
DR OrthoDB; 199953at2; -.
DR Proteomes; UP000295719; Unassembled WGS sequence.
DR GO; GO:0008840; F:4-hydroxy-tetrahydrodipicolinate synthase activity; IEA:TreeGrafter.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF66; 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000295719}.
FT ACT_SITE 141
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 168
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
SQ SEQUENCE 306 AA; 33023 MW; 2C36BE2C2CFFC167 CRC64;
MKDISESQAR LKGIFNITVT PFTRAGEFDY AGLARNIERV IGLGYDGILI GGTYGEFPAM
TATERAQMFR QVMEVVGDRV PVMLCSAGSD ARVVRELTEL AGSLGGLPMV TPPFVSEVTD
AQIVSFFRQM APLSRTGILV YNAPGIGITL PPVVLEQLAD IPGVVGIKQG DLNPTAIDQL
AHRLGGRLRL FCASDLAFLG PMMCGFDGIS TTNSGALPEL ILATYRALEQ GDAATARDLH
RLWYPYRALA RRLGQPQLVK AAMNLRGFDG QHVRPPLSDL NAEEVSLIEA ELHRLASDKR
SGVTLA
//
