ID A0A4S2KX63_9HYME Unreviewed; 430 AA.
AC A0A4S2KX63;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 18-JUN-2025, entry version 19.
DE SubName: Full=Homeobox protein SIX4 {ECO:0000313|EMBL:TGZ54266.1};
GN ORFNames=DBV15_06230 {ECO:0000313|EMBL:TGZ54266.1};
OS Temnothorax longispinosus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Temnothorax.
OX NCBI_TaxID=300112 {ECO:0000313|EMBL:TGZ54266.1, ECO:0000313|Proteomes:UP000310200};
RN [1] {ECO:0000313|EMBL:TGZ54266.1, ECO:0000313|Proteomes:UP000310200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole body {ECO:0000313|EMBL:TGZ54266.1};
RX PubMed=30967075;
RA Kaur R., Stoldt M., Jongepier E., Feldmeyer B., Menzel F.,
RA Bornberg-Bauer E., Foitzik S.;
RT "Ant behaviour and brain gene expression of defending hosts depend on the
RT ecological success of the intruding social parasite.";
RL Philos. Trans. R. Soc. Lond., B, Biol. Sci. 374:20180192-20180192(2019).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-
CC ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TGZ54266.1}.
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DR EMBL; QBLH01000792; TGZ54266.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4S2KX63; -.
DR STRING; 300112.A0A4S2KX63; -.
DR Proteomes; UP000310200; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IEA:TreeGrafter.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR CDD; cd00086; homeodomain; 1.
DR FunFam; 1.10.10.60:FF:000085; SIX homeobox 5; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR001356; HD.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR009057; Homeodomain-like_sf.
DR InterPro; IPR031701; SIX1_SD.
DR PANTHER; PTHR10390; HOMEOBOX PROTEIN SIX; 1.
DR PANTHER; PTHR10390:SF44; SIX HOMEOBOX 4; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF16878; SIX1_SD; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000310200};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 211..262
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 213..263
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 32..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 255..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 400..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..298
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 430 AA; 47900 MW; F57B9DE4D50F063E CRC64;
MSDSSDQLSS PNSDCNSQMG VVHRNATAQY SNTSSMSGLG LTHHPQNLTP TSNGSPQYSQ
ELSSCNSVSV NTNIGNIGGL SLNSSTNDFT PEQISCMCEA LSQSQDIEKL SRFLWSLPPG
ELLRGGESVL MARAAVAFYR GAYHELYSIL ESHAFSPRRH PELQQMWFKS HYREAEKIRG
RPLGAVDKYR LRKKYPLPKT IWDGEETVYC FKERSRNALK ECYMRNRYPT PDEKKNLAKK
TGLTLTQVSN WFKNRRQRDR TPQTRTDMLP LNCQGTTNST ISSSVSNGGS IQSLQSIDSD
SPNLAMSPLS TMGMSPVTMN PCSPMGMSPM GPHHGYATPV TPASVHTAHP HNGGLSPMND
VKTLCYGRGV YDTGKDVEQS SVYYSSHSSM HHQYYQQTHH QMMSSSHHHH HHHQQSVPAG
YEIMLPPPSM
//
