ID A0A4S2MMB3_9PEZI Unreviewed; 504 AA.
AC A0A4S2MMB3;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 28-JAN-2026, entry version 19.
DE SubName: Full=Sphingosine kinase {ECO:0000313|EMBL:TGZ76289.1};
GN ORFNames=EX30DRAFT_345010 {ECO:0000313|EMBL:TGZ76289.1};
OS Ascodesmis nigricans.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Ascodesmidaceae; Ascodesmis.
OX NCBI_TaxID=341454 {ECO:0000313|EMBL:TGZ76289.1, ECO:0000313|Proteomes:UP000298138};
RN [1] {ECO:0000313|EMBL:TGZ76289.1, ECO:0000313|Proteomes:UP000298138}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 389.68 {ECO:0000313|EMBL:TGZ76289.1,
RC ECO:0000313|Proteomes:UP000298138};
RG DOE Joint Genome Institute;
RA Lutkenhaus R., Traeger S., Breuer J., Kuo A., Lipzen A., Pangilinan J.,
RA Dilworth D., Sandor L., Poggeler S., Barry K., Grigoriev I.V.,
RA Nowrousian M.;
RT "Comparative genomics and transcriptomics to analyze fruiting body
RT development in filamentous ascomycetes.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; ML220187; TGZ76289.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4S2MMB3; -.
DR FunCoup; A0A4S2MMB3; 594.
DR STRING; 341454.A0A4S2MMB3; -.
DR InParanoid; A0A4S2MMB3; -.
DR OrthoDB; 3853857at2759; -.
DR Proteomes; UP000298138; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0016020; C:membrane; IEA:TreeGrafter.
DR GO; GO:0001727; F:lipid kinase activity; IEA:TreeGrafter.
DR GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:UniProtKB-ARBA.
DR GO; GO:0046512; P:sphingosine biosynthetic process; IEA:TreeGrafter.
DR Gene3D; 2.60.200.40; -; 1.
DR Gene3D; 3.40.50.10330; Probable inorganic polyphosphate/atp-NAD kinase, domain 1; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR055916; DUF7493.
DR InterPro; IPR050187; Lipid_Phosphate_FormReg.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR PANTHER; PTHR12358:SF31; ACYLGLYCEROL KINASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR Pfam; PF24321; DUF7493; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:TGZ76289.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000298138};
KW Transferase {ECO:0000313|EMBL:TGZ76289.1}.
FT DOMAIN 134..273
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
SQ SEQUENCE 504 AA; 55003 MW; FB3F63E3A349C1C6 CRC64;
MSTALLQSES TALSDSPSIS KELSLVLDPY LSLTIQGDEI RIVDRTPGKA TRKSARSCCG
VHATTNTSGQ DISIPFYNVL WTSADENCLT ITSADKVKKG VIPRTRTYTF DPVLQYTVKA
FVSKLLEAVY GSAKSRKRLK VLVNPFGGQG LATKIFETQC HSIFNAAQCE LSIQTTTYSG
EAVEIAERLD IDAFDAVVCC SGDGVPHEVF NGLAKRPDAA TALKKVAVCQ LPGGSGNAMA
WNLTGSGNPS EVALAIVKSV RKPIDLISIT QGDRRILSFL SQSFGIIADC DLGTENLRWM
GDLRFTYGLL SRIIKQTVYP CDLAVKVVID DKELIRTHYR QGGYPGQSAR EDVDNKNMAL
PTLKFGTIND PLPVDWELVH HPIMGNFYAG NMAWVSANVN FFPASLPHDA MFDLICVDGT
VGRMKALKMI TAAETGAHFE MPHVLYRKVV GYRIIPHRRD GIAEEYISID GERIPFEPFQ
AEVHSGLGTV LAKGDGYTYH APGV
//
