ID A0A4S4BLP0_9BACL Unreviewed; 427 AA.
AC A0A4S4BLP0;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 18-JUN-2025, entry version 26.
DE SubName: Full=GHKL domain-containing protein {ECO:0000313|EMBL:THF74751.1};
GN ORFNames=E6C55_24395 {ECO:0000313|EMBL:THF74751.1};
OS Cohnella fermenti.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
OC Cohnella.
OX NCBI_TaxID=2565925 {ECO:0000313|EMBL:THF74751.1, ECO:0000313|Proteomes:UP000310636};
RN [1] {ECO:0000313|EMBL:THF74751.1, ECO:0000313|Proteomes:UP000310636}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC-MHH1044 {ECO:0000313|EMBL:THF74751.1,
RC ECO:0000313|Proteomes:UP000310636};
RA Lin S.-Y., Hung M.-H., Young C.-C.;
RT "Cohnella sp. nov. isolated from preserved vegetables.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:THF74751.1}.
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DR EMBL; SSOB01000038; THF74751.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4S4BLP0; -.
DR OrthoDB; 1634477at2; -.
DR Proteomes; UP000310636; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042802; F:identical protein binding; IEA:TreeGrafter.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR016120; Sig_transdc_His_kin_SpoOB.
DR InterPro; IPR039506; SPOB_a.
DR PANTHER; PTHR40448; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR40448:SF1; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF14689; SPOB_a; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55890; Sporulation response regulatory protein Spo0B; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000310636};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 295..425
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 427 AA; 47663 MW; BE7E384E990F4F8C CRC64;
MSLRARRLRM KKTIMIIALV IIAIVIQHVL YFLQTKHSLT ELLKRQSQSA SEQFEAYLNA
LPSADELQDS LALDRLLASV VSAQNDLLEI AAFDADHAIP ERIFGHYSFG TKQDADLMRK
AKSSNQAIFG IQTVQGQRIM KMFAPITLSL SSVDGSFPPS SLKVLIAVTS NYRFVQQALN
KLLVTMILTS GTISAALIDI VLIVRLISRA RARDIKTTQE NYIDNMKQLY ASVRGQQHDL
LNHMNAIHAL VALEKYEDLD NYTKELIGDI SFTSDILIIG QPAMSAIIHA KSLVAKQKQI
QFTFDFEGLS GYPIGVRSVD ITRIMGNLID NSFDAVIGME EGLRQVNIRG WIEGNKLYLT
ISNPGSITPE EAKSIFKPWY SLKKEHTGLG LSIVKQLVGK YKGSIHLNLE QPGQVRFDVM
LALFKGR
//
