ID A0A4S4GW61_9BACT Unreviewed; 894 AA.
AC A0A4S4GW61;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 02-APR-2025, entry version 22.
DE RecName: Full=4-alpha-glucanotransferase {ECO:0000256|ARBA:ARBA00020295};
DE EC=2.4.1.25 {ECO:0000256|ARBA:ARBA00012560};
DE AltName: Full=Amylomaltase {ECO:0000256|ARBA:ARBA00031423};
DE AltName: Full=Disproportionating enzyme {ECO:0000256|ARBA:ARBA00031501};
GN ORFNames=E5990_07430 {ECO:0000313|EMBL:THG48265.1};
OS Muribaculaceae bacterium.
OC Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
OC Muribaculaceae.
OX NCBI_TaxID=2498093 {ECO:0000313|EMBL:THG48265.1, ECO:0000313|Proteomes:UP000305401};
RN [1] {ECO:0000313|EMBL:THG48265.1, ECO:0000313|Proteomes:UP000305401}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NM86_A22 {ECO:0000313|EMBL:THG48265.1,
RC ECO:0000313|Proteomes:UP000305401};
RA Navarre W., Wong E., Huang K.C., Tropini C., Ng K., Yu B.;
RT "Microbes associate with the intestines of laboratory mice.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Transfers a segment of a (1->4)-alpha-D-glucan to a new
CC position in an acceptor, which may be glucose or a (1->4)-alpha-D-
CC glucan.; EC=2.4.1.25; Evidence={ECO:0000256|ARBA:ARBA00000439};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the disproportionating enzyme family.
CC {ECO:0000256|ARBA:ARBA00005684}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:THG48265.1}.
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DR EMBL; SSTG01000089; THG48265.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4S4GW61; -.
DR OrthoDB; 9811841at2; -.
DR Proteomes; UP000305401; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004134; F:4-alpha-glucanotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:2001070; F:starch binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd05467; CBM20; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR013784; Carb-bd-like_fold.
DR InterPro; IPR002044; CBM20.
DR InterPro; IPR003385; Glyco_hydro_77.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR32518; -; 1.
DR PANTHER; PTHR32518:SF3; 4-ALPHA-GLUCANOTRANSFERASE; 1.
DR Pfam; PF00686; CBM_20; 2.
DR Pfam; PF02446; Glyco_hydro_77; 1.
DR SMART; SM01065; CBM_2; 2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49452; Starch-binding domain-like; 2.
DR PROSITE; PS51166; CBM20; 2.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Transferase {ECO:0000256|ARBA:ARBA00022676}.
FT DOMAIN 1..100
FT /note="CBM20"
FT /evidence="ECO:0000259|PROSITE:PS51166"
FT DOMAIN 125..241
FT /note="CBM20"
FT /evidence="ECO:0000259|PROSITE:PS51166"
SQ SEQUENCE 894 AA; 103571 MW; C2893B8326A2A24E CRC64;
MKINFNIDYK TQWGETLYIC GNDSLLGSGN IDAALKMHVD GVGLWTATVD ISDKNVRNLE
YGYVVRNDNG SERREWGGCC HSIDLSNAAE SYDIYDAWRD IPLDKPYYSS AFTQCINRRN
DRCEAVVPAP GFLTLSVDAP TVGPDEVLAL CGACDSLGEW NPEKALPMSD AGYPVWKINI
DLSRTILPIE FKFIVLDKDT RALKAWDGGD NRRLASMTKN RHVSMVVSGM RFRDPRALWR
GAGVAIPVFS VRTRDDFGVG DFYSLTKMVD WAVATGQKFL QILPINDTTM THTWTDSYPY
NACTSFGLHP MYMHLQELGR LKDKARQAYF DDLACELNNL PTVDYERVNE GKLQFISEIF
AQEGAKTLNS SDFTKFLIDN EYWLKPYAAF CVLRDKFGTP EFGKWGEYAE YTQAKADRVY
AENTPQMNQV YYTQYHLDRQ MRRVHEYASA HGVAFKGDIP IGISRDSADA WINPRLFNLD
CQAGAPPDDF SVLGQNWGLP TYNWEEMWKD RFAWWKSRFC KMAEYFDAYR IDHVLGFFRI
WQIPMTAVHG LLGIFNPALP YSADELKSLY DFWIDADVHT KPFIMDWFLN DFFGEYTDEA
RERFLNGLGH GRYELKSGFD TQRKIADYFS SQDKTEKNRR MCEALLGLAD QVLFIEDPDR
KGKYHPRISA QYTYVYRQLN DYEKWCFNRL YNDFFYHRHN DYWYGKAMWK LPNLIDATPM
LTCAEDLGMI PACVPAVMDQ LRILSLEIQR MPKDPSAKFG NTWNYPYLSV CTTSTHDMGG
IRQWWEDNPQ MAQEFYNEVL HQEGSAPRVA EPWICDQILN LNLKSPSMLA ILPLQDWLSV
SPDLRRPDPF EEQINEPSNP RHYWRYRMHL NVEDLLGAET FNRDLADRVH NSGR
//
