ID A0A4U6QJT6_9ACTN Unreviewed; 612 AA.
AC A0A4U6QJT6;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 28-JAN-2026, entry version 25.
DE SubName: Full=Selenocysteine-specific translation elongation factor {ECO:0000313|EMBL:TKV60747.1};
GN ORFNames=FDO65_03445 {ECO:0000313|EMBL:TKV60747.1};
OS Nakamurella flava.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Nakamurellales;
OC Nakamurellaceae; Nakamurella.
OX NCBI_TaxID=2576308 {ECO:0000313|EMBL:TKV60747.1, ECO:0000313|Proteomes:UP000306985};
RN [1] {ECO:0000313|EMBL:TKV60747.1, ECO:0000313|Proteomes:UP000306985}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N5BH11 {ECO:0000313|EMBL:TKV60747.1,
RC ECO:0000313|Proteomes:UP000306985};
RA Tuo L.;
RT "Nakamurella sp. N5BH11, whole genome shotgun sequence.";
RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TKV60747.1}.
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DR EMBL; SZZH01000001; TKV60747.1; -; Genomic_DNA.
DR RefSeq; WP_137448050.1; NZ_SZZH01000001.1.
DR AlphaFoldDB; A0A4U6QJT6; -.
DR OrthoDB; 9803139at2; -.
DR Proteomes; UP000306985; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:TKV60747.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000313|EMBL:TKV60747.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000306985}.
FT DOMAIN 4..130
FT /note="Tr-type G"
FT /evidence="ECO:0000259|Pfam:PF00009"
FT DOMAIN 195..263
FT /note="Translation elongation factor EFTu-like"
FT /evidence="ECO:0000259|Pfam:PF03144"
FT DOMAIN 291..351
FT /note="Selenocysteine-specific elongation factor beta-
FT barrel"
FT /evidence="ECO:0000259|Pfam:PF25461"
FT DOMAIN 550..595
FT /note="Elongation factor SelB fourth winged-helix"
FT /evidence="ECO:0000259|Pfam:PF09107"
SQ SEQUENCE 612 AA; 64210 MW; 30682CA4E16B905E CRC64;
MFVVATAGHV DHGKSTLVRA LTGMEPDRWA EERRRGLTID LGFAWTTLPS GRPVAFVDVP
GHERFLGNML AGLGPTPVVC FVVAADEGWR AQSDDHRDAV AALGIGHGLI AITRADRAAD
GGARALAQAR EALATTGLAG APAVHLALPG PPDSARGLDL VRQALDDVLD GVPEPPAGGR
VRLWIDRSFP VTGAGTVVTG TLAAGTLRRG DRMELWTADG ARDVTVRGLQ TRGGPQPEIA
PVNRVGVNVR GAAANQVGRG DTLLTPEAWP ITTTVDVRRV TGPALTDVPA TLTVHVGTAA
RPARLRPFDD DHGRLVLDRP LPLTLGDRMV LREPSRGIVG GVRILDADPP ALRRRGDGTR
RAAALRTLPV AGDPAFEVRR RGAVRPAELL RLGILDAETA EPPDGVVASA GWWVDAATHA
TWSRRLIDRV TTVLAADPLS AGLPEGAAVD LLGLPNPALL PGLVVASGLQ RSGGQLRTRE
PVGLGPTEQA IAALETRLGI SPFAAPEADD LAALGLGVRE LAAAERIGRL LRLPDGVVLL
PNAPARAMRL LAALPQPFTT SAARTALDTT RRVVIPLLEH LDTRGWTRRV DTGHRMVVGA
GRGSPPRSGD AR
//
