ID A0A4V1V375_9RHOB Unreviewed; 196 AA.
AC A0A4V1V375;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 02-APR-2025, entry version 17.
DE RecName: Full=acyl-homoserine-lactone synthase {ECO:0000256|ARBA:ARBA00012340};
DE EC=2.3.1.184 {ECO:0000256|ARBA:ARBA00012340};
GN ORFNames=EU803_00320 {ECO:0000313|EMBL:RYG93342.1};
OS Loktanella sp. IMCC34160.
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Rhodobacterales; Roseobacteraceae; Loktanella.
OX NCBI_TaxID=2510646 {ECO:0000313|EMBL:RYG93342.1, ECO:0000313|Proteomes:UP000294096};
RN [1] {ECO:0000313|EMBL:RYG93342.1, ECO:0000313|Proteomes:UP000294096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMCC34160 {ECO:0000313|EMBL:RYG93342.1,
RC ECO:0000313|Proteomes:UP000294096};
RA Jang H.-J.;
RT "Loktanella sp IMCC34160, Genome.";
RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a fatty acyl-[ACP] + S-adenosyl-L-methionine = an N-acyl-L-
CC homoserine lactone + S-methyl-5'-thioadenosine + holo-[ACP] + H(+);
CC Xref=Rhea:RHEA:10096, Rhea:RHEA-COMP:9685, Rhea:RHEA-COMP:14125,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:17509, ChEBI:CHEBI:55474,
CC ChEBI:CHEBI:59789, ChEBI:CHEBI:64479, ChEBI:CHEBI:138651;
CC EC=2.3.1.184; Evidence={ECO:0000256|ARBA:ARBA00048576};
CC -!- SIMILARITY: Belongs to the autoinducer synthase family.
CC {ECO:0000256|PROSITE-ProRule:PRU00533}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RYG93342.1}.
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DR EMBL; SELP01000001; RYG93342.1; -; Genomic_DNA.
DR RefSeq; WP_129680103.1; NZ_SELP01000001.1.
DR AlphaFoldDB; A0A4V1V375; -.
DR OrthoDB; 6169313at2; -.
DR Proteomes; UP000294096; Unassembled WGS sequence.
DR GO; GO:0061579; F:N-acyl homoserine lactone synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009372; P:quorum sensing; IEA:UniProtKB-UniRule.
DR GO; GO:0007165; P:signal transduction; IEA:TreeGrafter.
DR Gene3D; 3.40.630.30; -; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR018311; Autoind_synth_CS.
DR InterPro; IPR001690; Autoind_synthase.
DR PANTHER; PTHR39322; ACYL-HOMOSERINE-LACTONE SYNTHASE; 1.
DR PANTHER; PTHR39322:SF1; ISOVALERYL-HOMOSERINE LACTONE SYNTHASE; 1.
DR Pfam; PF00765; Autoind_synth; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR PROSITE; PS00949; AUTOINDUCER_SYNTH_1; 1.
DR PROSITE; PS51187; AUTOINDUCER_SYNTH_2; 1.
PE 3: Inferred from homology;
KW Autoinducer synthesis {ECO:0000256|ARBA:ARBA00022929, ECO:0000256|PROSITE-
KW ProRule:PRU00533};
KW Quorum sensing {ECO:0000256|ARBA:ARBA00022654, ECO:0000256|PROSITE-
KW ProRule:PRU00533}; Reference proteome {ECO:0000313|Proteomes:UP000294096};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
SQ SEQUENCE 196 AA; 22660 MW; 26039D63AE8A6CFF CRC64;
MYSTTLSFAN MHNHGELFVN ILRARRESFI VRNQWDLPET MGMEYDQYDT PQSRWLAVHD
DTGRVLAGVR LTPTTARCGI YSYMIRDAQN GLLDSIPEDL LFETAPVDEG TWEVTRGFVA
HDIPASIRHR VRMRLVLQML RTSREEGIRR MLALLPSNWH RWAARCSLEM SAAGRNMNMG
GIDYQAVWID FSTQLH
//
