ID A0A4V3DZ21_9HYPH Unreviewed; 886 AA.
AC A0A4V3DZ21;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 02-APR-2025, entry version 17.
DE SubName: Full=Ca2+-binding RTX toxin-like protein {ECO:0000313|EMBL:TDR94849.1};
GN ORFNames=EV668_2139 {ECO:0000313|EMBL:TDR94849.1};
OS Enterovirga rhinocerotis.
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Hyphomicrobiales; Methylobacteriaceae; Enterovirga.
OX NCBI_TaxID=1339210 {ECO:0000313|EMBL:TDR94849.1, ECO:0000313|Proteomes:UP000295122};
RN [1] {ECO:0000313|EMBL:TDR94849.1, ECO:0000313|Proteomes:UP000295122}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25903 {ECO:0000313|EMBL:TDR94849.1,
RC ECO:0000313|Proteomes:UP000295122};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDR94849.1}.
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DR EMBL; SNZR01000011; TDR94849.1; -; Genomic_DNA.
DR RefSeq; WP_133769707.1; NZ_SNZR01000011.1.
DR AlphaFoldDB; A0A4V3DZ21; -.
DR OrthoDB; 7975253at2; -.
DR Proteomes; UP000295122; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR CDD; cd04277; ZnMc_serralysin_like; 1.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR Gene3D; 2.150.10.10; Serralysin-like metalloprotease, C-terminal; 3.
DR InterPro; IPR018511; Hemolysin-typ_Ca-bd_CS.
DR InterPro; IPR001343; Hemolysn_Ca-bd.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR013858; Peptidase_M10B_C.
DR InterPro; IPR050557; RTX_toxin/Mannuronan_C5-epim.
DR InterPro; IPR003995; RTX_toxin_determinant-A.
DR InterPro; IPR034033; Serralysin-like.
DR InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR PANTHER; PTHR38340; S-LAYER PROTEIN; 1.
DR PANTHER; PTHR38340:SF1; S-LAYER PROTEIN; 1.
DR Pfam; PF00353; HemolysinCabind; 5.
DR Pfam; PF08548; Peptidase_M10_C; 1.
DR Pfam; PF13583; Reprolysin_4; 1.
DR PRINTS; PR00313; CABNDNGRPT.
DR PRINTS; PR01488; RTXTOXINA.
DR SUPFAM; SSF51120; beta-Roll; 4.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR PROSITE; PS00330; HEMOLYSIN_CALCIUM; 4.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000295122};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Toxin {ECO:0000256|ARBA:ARBA00022656};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT DOMAIN 765..817
FT /note="Peptidase M10 serralysin C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08548"
FT REGION 641..671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..657
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 886 AA; 90952 MW; 64D2FB6F510A2389 CRC64;
MATLSITPQQ IDNGLLYPNF YWPAGTITYS VPDGDTLWAS NYGSSEPTTG YSEFNAAQAA
QFVAAIELWD SYIANSMVRV DDGATYGDIR GAFTDIADPQ VGGQANAPPF QGNRSSAREG
DVWIDTTRTG SGFATGTQDF QLLLHEIGHA LGLKHPFETP TLPAEYDNHA YTVMSYTPAD
HRIIFSGGGG SIFWSQAPTA DKTPMVLDIA AIQSRYGADT QTGAGSTTYA FTDADLEARQ
AIYDASGNDT IDLSALSRGS TLDLRPGSYS DLAYYAKADQ IADTKARFPG FESFIENGFN
QPGVAVYEWT RNVGIAFSTV IENAMGSAFA DTIIGNSAAN RIGGGLGRDV LTGGGGSDNF
HGTAAALAGD RITDLSNGET ITLDGSTASI TAVSLASGTL TVSYRASAGG SVQSFAMTVS
GGVSGVSFSG RTITFGEADR NDTFVGQAGN QTYDGGAGID TVNYAAASGA LTVDLALTGF
QSVGGGFGSD RLLSIENLRG GTGSDRLSGS ASANTIWGGA GNDTILGRNG ADILWGEAGN
DILDGGAGAD RMFGGAGNDT YIVDAASDSV REDRIAGTDD GGIDLVKASV THTLRAFVEN
LTLTGSGAIF GTGNALANTI IGNDAANRLY GKDGNDRLDG RAGNDLLRGG NGNDTLTGGA
GADDMDGENG SDTYYVDASD TVRDRGASGI DTVIASSTFS LKGGDGIENL RLATNATSGN
LTGNELGNAI TAYGGNNVLL GLAGNDTIRA GAGNDTLRGG LGADRLYGEA GADTFVFAKG
ESLAVAGATD IIHDFTTRVD HIDLAIVSGS AAAAFYTEVK VASDSFTALK NAAEAAMSGS
QRIVFVAGTT DGWLFWSTNG SDGTVEEAVR LTGRNSLAGF DRADLI
//
