ID A0A4W4G2R8_ELEEL Unreviewed; 440 AA.
AC A0A4W4G2R8;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2025, sequence version 2.
DT 28-JAN-2026, entry version 26.
DE RecName: Full=DM2 domain-containing protein {ECO:0000259|PROSITE:PS51925};
GN Name=smarcd3a {ECO:0000313|Ensembl:ENSEEEP00000030934.2};
OS Electrophorus electricus (Electric eel) (Gymnotus electricus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Gymnotiformes;
OC Gymnotoidei; Gymnotidae; Electrophorus.
OX NCBI_TaxID=8005 {ECO:0000313|Ensembl:ENSEEEP00000030934.2, ECO:0000313|Proteomes:UP000314983};
RN [1] {ECO:0000313|Proteomes:UP000314983}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24970089;
RA Gallant J.R., Traeger L.L., Volkening J.D., Moffett H., Chen P.H.,
RA Novina C.D., Phillips G.N.Jr., Anand R., Wells G.B., Pinch M., Guth R.,
RA Unguez G.A., Albert J.S., Zakon H.H., Samanta M.P., Sussman M.R.;
RT "Nonhuman genetics. Genomic basis for the convergent evolution of electric
RT organs.";
RL Science 344:1522-1525(2014).
RN [2] {ECO:0000313|Proteomes:UP000314983}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28695212;
RA Traeger L.L., Sabat G., Barrett-Wilt G.A., Wells G.B., Sussman M.R.;
RT "A tail of two voltages: Proteomic comparison of the three electric organs
RT of the electric eel.";
RL Sci. Adv. 3:e1700523-e1700523(2017).
RN [3] {ECO:0000313|Ensembl:ENSEEEP00000030934.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Myers G., Meyer A., Fedrigo O., Formenti G., Rhie A., Tracey A., Sims Y.,
RA Jarvis E.D.;
RT "Electrophorus electricus (electric eel) genome, fEleEle1, primary
RT haplotype.";
RL Submitted (MAY-2020) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|Ensembl:ENSEEEP00000030934.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [5] {ECO:0000313|Ensembl:ENSEEEP00000030934.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SMARCD family.
CC {ECO:0000256|ARBA:ARBA00010619}.
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DR AlphaFoldDB; A0A4W4G2R8; -.
DR Ensembl; ENSEEET00000031302.2; ENSEEEP00000030934.2; ENSEEEG00000014786.2.
DR GeneTree; ENSGT00940000158945; -.
DR Proteomes; UP000314983; Chromosome 18.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-ARBA.
DR FunFam; 1.10.245.10:FF:000001; SWI/SNF-related matrix-associated regulator of chromatin subfamily D member 3 isoform 1; 1.
DR Gene3D; 1.10.245.10; SWIB/MDM2 domain; 1.
DR InterPro; IPR019835; SWIB_domain.
DR InterPro; IPR036885; SWIB_MDM2_dom_sf.
DR InterPro; IPR003121; SWIB_MDM2_domain.
DR PANTHER; PTHR13844; SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D; 1.
DR Pfam; PF02201; SWIB; 1.
DR SMART; SM00151; SWIB; 1.
DR SUPFAM; SSF47592; SWIB/MDM2 domain; 1.
DR PROSITE; PS51925; SWIB_MDM2; 1.
PE 3: Inferred from homology;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000314983}.
FT DOMAIN 215..292
FT /note="DM2"
FT /evidence="ECO:0000259|PROSITE:PS51925"
FT REGION 1..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 440 AA; 51011 MW; 3BD496D5B3C486A5 CRC64;
MYRCHSRPGL TSGARMPHQG APMGPPGLPY GGTAPVRPVM PSPVLDPNRK RPTPTPPVQA
PPVQNRPRSA KRRKMADKIL PQRIRELVPE SQAYMDLLAF ERKLDQTIMR KRVDIQEALK
RPMKQKRKLR LYISNTFNPS KPDSDDSEGS IASWELRVEG KLKISCLFYS CFCCLFCLLY
KQWHRTPTTQ ETDGFQVKRP GDVNVRCTLL LMLDYQPPQF KLDPRLARVL GIHTHARSCI
IQALWQYIKT NKLQDSHEKE YINCDKYFQQ IFDCPRLKFC EIPQRLTNLL LPADPIVINH
VISVDPSDHK KTACYDIDVE VDDPLKTQMS GFLLSTANQQ EIASLENKIH ETIESINQLK
IQRDFMLSFS RDPKGYIQDW ICSQNRDLKL MTDVLGSPEA ERKAEFYNQP WSQEAVSRYF
YCKIQQRRQE LEQALAMRTT
//
