ID A0A4W5LCU3_9TELE Unreviewed; 708 AA.
AC A0A4W5LCU3;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 28-JAN-2026, entry version 27.
DE SubName: Full=Collagen, type XV, alpha 1b {ECO:0000313|Ensembl:ENSHHUP00000023667.1};
OS Hucho hucho (huchen).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Hucho.
OX NCBI_TaxID=62062 {ECO:0000313|Ensembl:ENSHHUP00000023667.1, ECO:0000313|Proteomes:UP000314982};
RN [1] {ECO:0000313|Proteomes:UP000314982}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Macqueen D.J., Gundappa M.K.;
RT "Genome assembly of Danube salmon.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSHHUP00000023667.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [3] {ECO:0000313|Ensembl:ENSHHUP00000023667.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
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DR AlphaFoldDB; A0A4W5LCU3; -.
DR STRING; 62062.ENSHHUP00000023667; -.
DR Ensembl; ENSHHUT00000024559.1; ENSHHUP00000023667.1; ENSHHUG00000014855.1.
DR GeneTree; ENSGT00940000164061; -.
DR Proteomes; UP000314982; Unassembled WGS sequence.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR CDD; cd00247; Endostatin-like; 1.
DR FunFam; 3.10.100.10:FF:000008; collagen alpha-1(XVIII) chain isoform X1; 1.
DR FunFam; 3.40.1620.70:FF:000003; Collagen type XVIII alpha 1; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050938; Collagen_Structural_Proteins.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR37456:SF6; COLLAGEN ALPHA-1(XXIII) CHAIN-LIKE ISOFORM X2; 1.
DR PANTHER; PTHR37456; SI:CH211-266K2.1; 1.
DR Pfam; PF01391; Collagen; 4.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Reference proteome {ECO:0000313|Proteomes:UP000314982}.
FT DOMAIN 432..479
FT /note="Collagen type XV/XVIII trimerization"
FT /evidence="ECO:0000259|Pfam:PF20010"
FT DOMAIN 533..702
FT /note="Collagenase NC10/endostatin"
FT /evidence="ECO:0000259|Pfam:PF06482"
FT REGION 1..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 147..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 231..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 486..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..17
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..108
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..125
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..279
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..292
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..343
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..406
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..423
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..495
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 708 AA; 72059 MW; 8BB591E96C1966A7 CRC64;
MKGDPGPRGL PGPPGPPGGG FFVEDVEGSG KNDMVLGTEL KGPQGPPGLP GTAGPKGEDG
KDGAPGLSVK GEPGASGPEG LQGLAGLPGA RGLKGDKGDP GPKGECGPDG HNVPGPPGPP
GPPGPIINLQ DLLLNNTEGM FNITEIRGSP GPMGPEGEPG RAGFPGPRGP KGDSGLPGFQ
GPPGMKGVKG EAGVTIAADG TVLTSVRGPQ GPKGIKGERG FPGAYGVMGP IGPSGQKGEY
GFPGRPGRPG MAGKKGDQGD AIGQPGLPGP PGPPGPPGPV TGLNGVNGSK GSSQGGRRGN
RGAKGEKGEV GLPGMPGEPD DILPEGFVGE KGDVGYEGMK GDQGEPGLPG PPGLPGRSGL
VGPKGESVVG NVGHPGAPGE PGIPGIGRPG SRGPPGPAGP PGPPPVYGSA VSIPGPPGPP
GPPGITGYEN PVSTYRNTNT LMRESHRAAE GSMAYVSDKG ELYVRTRDGW RKVQLGELIL
VPAESPSSAV SQSLSRPGDR TRPNRPHSQE LVGTSYVPNY NVLPHTVHSV PALHLVALNA
PFSGDMRGIR GADFQCYQQA RAMGLTATYR AFLSSHLQDL ATIVKKGDRY NMPVINLKGE
VIYSSWMNIF SGNGGVFDPS IPIYSFEGRN VMTDSTWPQK LVWHGSSTVG IRMTTNYCEA
WRAGDMAVTG QASLLQTGRL LGQHTRSCSN HFIVLCIENS YVDHRRSN
//
