ID A0A4W5M4R5_9TELE Unreviewed; 658 AA.
AC A0A4W5M4R5;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 28-JAN-2026, entry version 27.
DE SubName: Full=Collagen, type XV, alpha 1b {ECO:0000313|Ensembl:ENSHHUP00000032834.1};
OS Hucho hucho (huchen).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Hucho.
OX NCBI_TaxID=62062 {ECO:0000313|Ensembl:ENSHHUP00000032834.1, ECO:0000313|Proteomes:UP000314982};
RN [1] {ECO:0000313|Proteomes:UP000314982}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Macqueen D.J., Gundappa M.K.;
RT "Genome assembly of Danube salmon.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSHHUP00000032834.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [3] {ECO:0000313|Ensembl:ENSHHUP00000032834.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR AlphaFoldDB; A0A4W5M4R5; -.
DR STRING; 62062.ENSHHUP00000032834; -.
DR Ensembl; ENSHHUT00000034172.1; ENSHHUP00000032834.1; ENSHHUG00000020786.1.
DR GeneTree; ENSGT00940000164061; -.
DR Proteomes; UP000314982; Unassembled WGS sequence.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0031012; C:extracellular matrix; IEA:TreeGrafter.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR CDD; cd00247; Endostatin-like; 1.
DR FunFam; 3.10.100.10:FF:000008; collagen alpha-1(XVIII) chain isoform X1; 1.
DR FunFam; 3.40.1620.70:FF:000003; Collagen type XVIII alpha 1; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050149; Collagen_superfamily.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF1082; COLLAGEN TRIPLE HELIX REPEAT; 1.
DR Pfam; PF01391; Collagen; 3.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000314982};
KW Secreted {ECO:0000256|ARBA:ARBA00022530}.
FT DOMAIN 385..433
FT /note="Collagen type XV/XVIII trimerization"
FT /evidence="ECO:0000259|Pfam:PF20010"
FT DOMAIN 483..652
FT /note="Collagenase NC10/endostatin"
FT /evidence="ECO:0000259|Pfam:PF06482"
FT REGION 28..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 186..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..63
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..78
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..232
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..247
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..298
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..359
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 367..376
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 658 AA; 67595 MW; 39253AF51F019A3D CRC64;
MDIDGCVFHI LCNLSCLQLH SVSFQGEPGA PGPEGLQGLA GLPGARGLKG DKGDPGPKGE
CGSDGHNVPG PPGPPGSPGP IINLQDLLLN DTEGMFNQIR GPPGPMGPEG EPGRAGFPGP
RGPKGDIGLP GLHGPPGMKG AKGESGVTIA ADGTVLTGVR GPQGPKGIKG ERGFPGVAGI
MGPIGPTGQK GEYGFPGRPG RPGMAGKKGD KGDAIGQPGL PGPPGPPGPP GPVIGLNGVN
GSRGSSRGSR RGNRGAKGEK GEIGLPGTPG EPDDVLPEGF VGEKGDVGYE GMKGEKGDGG
LPGPPGLPGR SGLVGPKGES IVGAPGHPGA PGEPGLPGIG RPGTRGPPGP AGPPGPPPVY
ASAVSIPGPP GPPGPPGITG YENPVTTYRN TITLMRESHR AAEGSMAYVS DKGELYVRAR
DGWRKVQLGE LIPVPAETPS SALSQALRRP GDRSRPHRQE LVGTSYMPNY NVLPHTVRSV
PGLHLVALNA PFSGDMRGIR GADFQCYQQA RALGLTATYR AFMSSHLQDL ATIVKKGDRY
SMPVINLKGE VLYGSWMNIF SGNGGVLDPS IPIYSFDGRN VMTDPTWPQK LVWHGSSTVG
IRMTTNYCEA WRAGDMAVTG QASLLQTGRL LGQHTRSCSN RFVVLCIENS YIDHRRSN
//
