ID A0A4Y2F912_ARAVE Unreviewed; 8522 AA.
AC A0A4Y2F912;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 18-JUN-2025, entry version 19.
DE SubName: Full=E3 ubiquitin-protein ligase RNF31 {ECO:0000313|EMBL:GBM37973.1};
GN Name=Rnf31_0 {ECO:0000313|EMBL:GBM37973.1};
GN ORFNames=AVEN_171161_1 {ECO:0000313|EMBL:GBM37973.1};
OS Araneus ventricosus (Orbweaver spider) (Epeira ventricosa).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC Araneomorphae; Entelegynae; Araneoidea; Araneidae; Araneus.
OX NCBI_TaxID=182803 {ECO:0000313|EMBL:GBM37973.1, ECO:0000313|Proteomes:UP000499080};
RN [1] {ECO:0000313|EMBL:GBM37973.1, ECO:0000313|Proteomes:UP000499080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=31182776;
RA Kono N., Nakamura H., Ohtoshi R., Moran D.A.P., Shinohara A., Yoshida Y.,
RA Fujiwara M., Mori M., Tomita M., Arakawa K.;
RT "Orb-weaving spider Araneus ventricosus genome elucidates the spidroin gene
RT catalogue.";
RL Sci. Rep. 9:8380-8380(2019).
CC -!- SIMILARITY: Belongs to the RBR family. {ECO:0000256|ARBA:ARBA00008278}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBM37973.1}.
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DR EMBL; BGPR01000855; GBM37973.1; -; Genomic_DNA.
DR OrthoDB; 6435653at2759; -.
DR Proteomes; UP000499080; Unassembled WGS sequence.
DR GO; GO:0071797; C:LUBAC complex; IEA:InterPro.
DR GO; GO:0036435; F:K48-linked polyubiquitin modification-dependent protein binding; IEA:TreeGrafter.
DR GO; GO:0070530; F:K63-linked polyubiquitin modification-dependent protein binding; IEA:TreeGrafter.
DR GO; GO:1990450; F:linear polyubiquitin binding; IEA:TreeGrafter.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0097039; P:protein linear polyubiquitination; IEA:TreeGrafter.
DR CDD; cd19815; Bbox1_HOIP; 1.
DR CDD; cd20337; BRcat_RBR_HOIP; 1.
DR Gene3D; 6.10.140.1100; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047543; Bbox1_RNF31-like.
DR InterPro; IPR047540; BRcat_RBR_RNF31-like.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR026254; RNF31-like.
DR InterPro; IPR032065; RNF31-UBA.
DR InterPro; IPR041031; RNF31_C.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR16004:SF2; E3 UBIQUITIN-PROTEIN LIGASE LUBEL; 1.
DR PANTHER; PTHR16004; RING FINGER PROTEIN 31-RELATED; 1.
DR Pfam; PF18091; E3_UbLigase_RBR; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF16678; UBA_HOIP; 1.
DR SMART; SM00647; IBR; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS01358; ZF_RANBP2_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000499080};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 8159..8391
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 8163..8212
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 79..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 461..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1306..1481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1888..1922
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2004..2033
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2055..2081
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2773..2792
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3295..3329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3347..3370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4079..4196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4421..4441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5903..5922
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6438..6461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6931..6956
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7034..7055
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7350..7512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7527..7575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7592..7629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7809..8090
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2713..2740
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3689..3716
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 385..397
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 469..478
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 498..508
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..518
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1314..1332
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1437..1458
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1462..1475
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1913..1922
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2067..2081
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4079..4089
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4126..4139
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4174..4189
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4426..4441
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5908..5919
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6931..6942
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7037..7046
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7354..7363
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7372..7493
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7536..7558
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7618..7629
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7812..7822
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7843..7852
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7853..7865
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7892..7908
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7912..7921
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7928..7980
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8005..8047
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8075..8089
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 8522 AA; 951323 MW; CFF6901D4BA2EF8F CRC64;
MEEAENSGDG PIPKNDDLLN SPAKSCALCG CSTPAVRCDR CSGQIFCLSC DDMYHKHPKR
RLHLRKAVDS IWNSARSPRL RRRTDLPGDP SKIPIPPPRS KKRERHTIGG RMFLKPNHEL
GSFGHSKVFD MRSLTPTSKD VFAGPKTPTS IEGTYENETA FPAHGVEEII KPNEIYENEN
VSVNQGETVD NSNSLVTNPW NVQRTNISSP IQVSIPSGSP DLMTNGQSFG YPLKPQSRSI
ADLTGAPANP MAPHPYHLPH YPYMHPPVHP PFSHSMAHLN CAQCLSSSWS NLMSPHPSPY
FHPMPWGSAQ GSLTRGQAPP ATNGNLRHSH GSIPTYPDPN FHYPYPGGPY YPNGAPPVDP
NFMRDLQQHA DESKMSKSSS KRSLNMENMD TAPSTTEGDV RNAEGGAATE VTGQVKPTTD
DEVPEIPPPP SKPWSCMHCT FVNPPGSHIC QVCCKTSYKT SASAPSDDQN ERSLHSRNSD
SPMELVNLDA ISQSPDLSEL REAQKCDESI GEDSLENEET CKQIPPSDAK EVPEASVMLC
TETQTFTTTK STDVQTQNLI CKSMASSTDS IFPKQEISVQ TETEMAAKHC SVATDPMISS
QSMESLLSGM SAPPYHNRRA GWGRGTSYST QSLFERGRSR SPIPRSLSMY NEAHSFGRDS
SLPPEEAMHS WSQAWLMSDP MYYKPHNLPG LGQPLAKEDY FDGTWGSMDK LNRRMKNKQG
EKLKSQQRPK LHRSLDDLKA EKTQDFIHSR ELQFLQTVKE AERCGFSLED LHVAFLHCGR
EDPVIWLEDN WSSMIKNVIA LAAKYGEDNE ENDVGVITAT EAKEALHIHR GDIWDAVTEC
IENRQRKILE LTVRGNFTQK QISDALKNNE GNIELAYADL LRASTKRHKF ILSPGLSEDS
DMYNPIDDGS TSLKTAKVDV STDSKTDKKK SDFLTKLSAI RQAQSERRKA REEKEMIRET
ATQEIPTTLD EPEIASPSME HEKEVDVQKE KVDVTTPELN TEAIQENIEK DLIEAELEFE
EPLKDSLEKK EVMEDNIPVD YDTNWVESQG EWIEEYSDEH WDEESDEHWI ALQKKYQKME
KEFEQEAIQM AALWEKEELS DDVFEDEPKE MLQPIQQSEA ERLRAEQDEK FQQWVKINLE
KSTSEPEDNE VTGLAINSDL LAQSSLSKSA EFDRNIICES PLTHYPPVFD LSKKPEPDWV
ELEVTGENTA LHDISTRDIE EVLNHELGEQ KILKDHEVKN EEYILNAGNS DEEWEKIDEN
ELLELKQDEE IMAPAGIDIS EQLRSEEILA DHPEEHKDIF ESHLFEDKIS EETSPVMHSE
SHISSSKPES SSAEINENKY QVSKEKSPEV GVPKPPVRRK SKLNTAAIEE ALRNQPQVDL
DVPPALPQKK KDKSPDKSAV MDLYAVPQKL HRDEKIDTPV VPAPLKPPRL NLSPSAEWER
QQPDEIEDKK FLNVEFSKEA SPVTSQSNES DSNCFADSES DPEIKIIRQK YMHRKPPKYE
NEDEELFEES FAKSEEVDSA KSLRHAVEEA SAAFEFNPEL PIPIGSRGSR IVDEMASPKA
FREGSARPLQ LFKVVKQEPS HAVSNKMEAE QILDTATVKN LHEERTPEHL PERAEQPVTS
ESLMNEFMSA EPHVETSQAT DSYYYNTEVM EQISKDSIPT PLQTSDLHYY NIEKMGNISP
SAASVPLQAD SSNYYNVEKI EHTTEDKKSP EVMEVQQEEI RIQSQPMNNI PAKFEETIPE
TSFHTQPESK EDDEIILPEL DIMPAAAEYF FGRYNEVTVA KPKKKSPVIK SNKPAGVPKV
MSTSEIKVPS PAKSLSPMEV NASPVMMSAD NKDKPMEIER KLDNLKSSAP IPPAVSAPEI
PPEPAATEYV SFAEDYFFGS YNEVVPKKAK KKPVTTAPKS KVADKPKLPD IASSPNELSS
KMTASSLETG ITGVNQANLS MTTSLPEALH QQSGNLIFDA NAQMMQTSVL TESLELPVNE
LSVQTAENDE MLDSKTKVIH FEELEPVAPP PRKKKSKPEP NMSSISSHTE EHRYMEHYDE
RRPLTMLDKK KLPPYSKDFR MNQGCDPSNL PSNSLLSSAE QQESVVSSDI SLHTSKEPFI
MEKEVLKMKE IENIDSQNFE IPSLDEVKDF SDSPSVYQLP LSFSDETVAP ESVYQSVGGL
FNPPIQLQEL QNFVLPITHE EVTSSKHSKM SEVTTMLSKD SSHECESKIN EIHSLDSELS
SDTAEKISHE FSKSYQTTSF ISENIPAALN TSVEDQKFEG RAPSDLELKV PKLSTIIESQ
IQESSKIPED ISVISEDNRI AFTLSQKLFE SVQQENIQSQ FSVFSKDQEL SRASKDDSSA
MRQNYEHEQA FIESSDIQIA EHSIILEDDS LIPEDTLSVL SFEHLATETS SSGLASALHA
RMEDSEENIP ISESLSEKSE IGGILQKDSE CDDESYDTQF RDTKLEDDYS ILQMDEDFDD
GLRLVEETEK LISEFCDIYP SECFDVSSNE IQNLNTKNNK QDSTYDSEYE WKLNEERYNS
LNANFIENKA YKMDITSTPS PDESKAPLII NTGTPTDNLE LNKSITESRK STSSLADISE
ISEFIEESNL TQAIKKNDIA GEDDVSLSVQ PLSVLCQAAT SNYQGVPAEI MPSGSLLLSE
KESLETVNEG SDDSLVTSTH SSVSTQIAVF ADTLLQDLTE ELGISLDNKT TEGLDEKSST
STNIPLNLTE TESLTAADKK EETEKEIAML NENVESDAAT EKEINDLPGF DSSEGRIMDS
EHYESEVVEE LDKESQIQQT EDKSINEPSD LDTVSSSVEF MEAPESEIIK KLVREIKTEN
IEELNTETEV EQAASSKQTA DELSEDVMAG KIDDLYISNL NAYGISDPEC DETLQDKTSD
DVPEEISLSL MSHFYDEWIG KTEEQLEIQQ SEEFNDETKI ELTEELNLAI AIEETEELMK
QIETDWTEDE TRESKDETRE TSDFEITANY PEESSLSLMS HFYDEWIENV KTSETQPAFQ
IDIRNLYVSN DFSESSSSGN VSENEDFASI SKTELTSELT DSNLNDAYVE SIAAVTKNEP
FKLLDQGAIY ISDEKGQTLV QEKFLSDTCV HDKNLFKSYD EERCSVAVIT ENEPVELSDQ
GAIHISDEKD QSPVQQIKVE KDVLNNISDN SDDSVPAVRD ISKHAEVEII DSFIEKMYSV
SKSCQTDDSF EEDQFFDSFD DPAFDPAFIF PPVLKCALTE PVRTEIGVQC CLIPSEIALI
SDVAVISLDS SERHKEVKKK EKEGNTEQIK DAIQADDEPA LQIFDVKKDG IIVSDSSTKQ
KEDSSSETTE DTDSDIFLEP YSSHDEFETD SKSKGYYLYA EIDSDTGFSS GSDSGRRSSK
QKSYSKETVH LRSQKVESEC LQGESTISDE VSVQMSEIST VETVEQKALH VTIKSESTIL
NKAEMQNNVD EKKGITLTEQ TKVTTEECIV SDGGVKIDLP QEILERAVTP ISIKRVPSIE
SDLKFVDIED ELEPSELNEQ VIETEVCEDR VKTPTVEYFH GPLPQSVQKE ILQENNECFV
EALELLDAYA AEVEKDISEN SFSTQLSDSK FSLPADSGDV EDFSESVGSF HEPEDDLLTE
SVSEYFGLPE SEGIPASESK VSRKFIKTEI ISQDSSTQVK SSESFCDEDK NPLKTHQELE
LKKVSTLEQQ KFIGDVSKSS PTNDIYENLD KIEVQKKTET TEKKNMKEAI AEIKTQQISN
SNVFPEKNAQ SILSANIPQL ESIESGIGTD RISSALEFEE SACSGTLSIN HPTNKPEKQI
SLSLPSEAEV ANILDEDEQK ESPADISTIC VDAQKESKEI CNVSELGDSL YADRKTDYFS
VEKTSSKKVS ESSPDTEDFY QKSITEYFSS EIDSANIEQA KSLGHLKDSK VSPSLEINSE
FINVDSDLTV SEAFDQSDYQ ETEISVYEES SEHFKNLNEF EISKQSEIPP VPSDIVRYLY
YDDSIKFEDD PSTCEDSLNS MHFVEQSSSM QESDIACKEV YSLDKGGQQD EFKAPNTSHS
CMSPSTQEPE KILSDICVKP SSSSLEVFSK ETNIAKADQD GPEKLATDIH LVEKKIQQES
ETLDKDHTIE SLSTLELEKI PSDISIKHPT HGLEESPNAL ADDGDLEKHA SGTHDEKVNK
MQQESEALGK SHSLESSSQL EPEKVSTDVS LEQPRSDQEE SPKKSKADDD GFEGVVSHFP
CSEEHKLQQH NTLDKGHSHE SSSAVELGKV SSDISVDKCN NPEEAAKELE ILQDQIKIDH
YNLEKLDKSH GNIDVIYPNE ESMEIALQES KSEAISHPIL HEKDTIEEIT TKPPEAEVSL
LSANNSQYEN PITELQEARR PSEIPSKPSD IVRYLYYDDS IKFEGDESFY DESFNSINSF
EPSSLPELEI VSDNVTTSNL CIDEKESLQE SLKLDVDEHR PKEHPLLPSE SFESPESGIS
SSSLENITDE QFIHSCDSEK DKFESVYSVS ESTEQWFDLE TSKSFQPCLE ESQISEGSDH
LTETKTTTQD GDLPCIPGLL LEGKAKDNAP IAVADCDDVT DISTHFTMTE DESDKFSDIE
SDSSVNNFDE EGLFAVDQNK NEVTDFEIDR ITDIEGDKEN VIQQDDLLDK NANKNEENYP
EECATPTDFE KQEQDIEASL RDVNGNLAEY IANSGVSGMV ENVGSETQEV DGIPKDQNIS
MQSTENEIYT APDAAVMRST PTESCKDEFF DISETEDSLN ISKTGPDNLP KNQNISVQIA
EIEICTTSDA AVMRPTPIES CKDEFFDISQ AEDSLNISKT RPDNVTKDQN ISIQFAESEI
CTTSDAAVMR STPTESCKDE FFDVSQAEDS LHVSITENLD NWIDAESGGL TETEEIKFNL
PEEGILETTS VSKMTDSLVK KEIYDISNKE NILSSDVQIT KIDDITIPAQ QEASLFVKTE
SPSKEPLSKT KEDMPADNVI SFASHEFSLD EGTRSEIVEE IYSSNLDAVK TCYVTEKSPA
SAYVSDVFES VTVLAKEDSN FYATIEQRDI SLETCGGFYE TKERDFDDFP KSLEALPNPV
SDVSGTECIP NFGTEGKISL PLDEDASLED KTDICAQLKT ASDPDDGKLK TDEIKSLDAQ
ESYVVDFKGI IDEQDNAILS CQLKDNSKKE AVSISISVEP NILKSDIEEA KTLPCQTVEL
LAPIDSYVKF SENISDETPD IGAKEIIISK TSVHDETIVD FKGIGNDSVL LSSQQRDSTE
KETVSDSQSV EHFESSILKS EAVVEEVVEK EKKFSSDTVH NEVTADFKGI IDDSQLFSNQ
QPYNLEKETV SISQSIEESN ICESKFKVTA NFEPLESTSP FEHNAEHNYL VKSTEDKDSI
FIAEDAEQGK CTVDFKGIVA DLELFSNEQK IVSDDKTLGA SPVVSDILKQ EIEISCSEIT
LLNTVEKESD KKYIEKTETV SSLVAAEDNI IVDFKGIISQ PELISDQQDS GIEGANFNSP
ASIGHIESNI LRSETKEIEE SHSEVSVSDA SLNTFSNAEN ECQIQFVEEN NTAILECAES
EKYIVDFKII SDSVLLNDSS NRVESIEQQN SSQLKDVSST TMGSLVSTIE SSSQEKMKEV
AISESDESIF DFKGIVSDSE VFSEKKLISE YVQQDEQNNG SVLNKDKIIF SDIDASLASS
ESEKIYDKKL SEEKVLPADI EQEICIVDFR GIAFDTELSS NKQKSDKKQE KFSISEYTEQ
LQQNITASEE DLEKITTQKQ LKKFSVSTDV NSSILDNKNL YEKTIKEIPR ESVNEMSMCS
ETDSSCFHSA LENIDNTSVF TSDDDFTDVH SHITLTEDSD RWSDVETDTS FAFEDFNQDS
FDMLREKTPT RDDYEYNFKL PTLNATPEPK IQEVSSKKMD FETDKEEISS TVEIEKQMLQ
HLNELEHATV LDSSVATLSS SLSDVKHQGT TSEKSTSLNI LPKSDELNVS KLEEPQKAET
PGVSELEGMC ESFPESSDNI TKIPATELVT DSLSKLDTVP PSFQPESVLS DDNADVMSFS
SITDECETWS DNEITASLTD QLKPSEKEEL KINIELSTDD LKSAVTVQDE VSPDTSKSIV
ECPSSELLND KETLNQISEI PSEAVPLETA LTTFESSLEP RTSPIISLSE ETKIPLPLSE
EVKLPSESVL EELKPLPASL SEEKLSSQSL SKEDILPLDS LPQNLVVPEA EIVKSFDSSR
ENSKTISSSG QNDLSFCTIS KEDSDAFSEL DAETSETSAS SFFETISKGD DSEKISNFGV
KNYGELESKA IFTEKFDEST VSFSDISMVD NQKSPSTETE EKKLPDSSCS SILHASVTKE
IYSTENIAVT EQFKEDIIKS ETESLDEPTF DILPEPVPLV VGKKALSLSI ADIVESSELS
IACDQTTEPL LLEQFADVKS LSHQVAMIEN FNAFETDTAV PKIHKETADV SLGVEKTEES
DNWLEAETEY SISEFEDEAV SFSDKGKPEL QPSETVDGSG ISEDKVNAFE TATQLSTEDM
TGISASFYTE SEYSDQVSDT FADISLQGGT TENSDRWSDI EAEDVINEVL SENIPIIDAK
ELITGFDLGL NGKQESTLQS EDIVEKESKL VEHLESNSGI SKELVSTSKV VEMKQELLDS
SLIKVESKDD SKINKHFSSA SEKLLDTASG VSDDDFTSVT PIDPTVGESD KWSDISDDTS
VEEMLDSSKS LSLQKGISSQ LDSKPKAAVS VDTVKKIDVD DTQLTADSLP KSQQLEQSES
YFDLPVETEV FEESHEKSNI DMESPSFSED QALLDDIPDN HVFLQEKAII AAVPSDISDT
SRNQLESTVA ADIQIQDDVY NCRTVPSPIY EDEEPLEGEE YFDEYDPNFD ENEMELAEED
YHTGSVPYIL NDDELVYPLQ YGDDWIEESF DLKEYGIETV FSGSEADVHG LNINEEFDED
IRRAIDFNIN NFEEAAESFI DDQNLTTESF KTLSDNTPTQ SKLTDKEHDS WSTADADSIA
DDHDDVLAKI DEILAEDFGY GKLDYFDDKQ GSRDVGRLIE EEEDDYYQDS PIDSPYKEET
ENLQVNNFVC QSSTETRSSE VAHRTSPDVP VTSEDSRLTE RYKEDSSFLF KDVFPSSNEI
TQFATDEMKE TVKMRKLSEE IFEANEALKE SLSSAASEKI VKLEGTTEKI DIAIKEPTEW
RLTPEKTEIS SSEVNSEFLS AATSVLPEVA LQSKSPEKVD TSLDEAVKLR PPSEEISASS
SEVMKLKSSS EKAVFSEEIV SLKVASNKID ISSEETVLQP STEIADLSSE EPAKLHSLDK
TDLPTEKVIK LRESSEEISV SSANIMGKSE ETVSLKASVD KTVTTSEGMN LKSQTEKVTL
PSEETVKLQA CIKNDLSMEK AVILKTSSEE IDVSSEKVVE KTSAKKSVPP KKIVENSSEK
EPLSPEKVVE RSPEKKSALQ EKVVEKSPEK KSLSSEKIVE KSSEKKPLSP EKVVEKSSEK
KSASQEKVVE KFSEKSVSEE EIVEKPSEKK SVLPEKEVEE SLEKALPSDE AKKLKTSLAP
ASSEETVKLK SSSEKVTVFV EDTVNLTSSK KSSLSSKEEL TLKLTAEKTD RPSEEAVKLK
SSPGKTSVSE EGDMELKKTE IFSEKILKLE TSSEKTGQSL EGEAPTLPPK KSSLLSEETV
KSKLSAEDGD LRAEKDIKLK EPSKEIDISS EITAKKSTKK MSISSNETVE LKSSPEKIST
SLEEAKKLEI APEVVPSSPD EVKKLKASSE KTNVPLEELE KSKSSLHKTA VSSEETVKLK
VTTEKTDVLS KDIVTQKSST ETDVLSLDKT VKLKTSSEKS CASSSEELVV KLPSEKATVF
SEEIIDSKLS SEKSSCNETV KLQSPLEKTV SSEETVESKA SLKKPDTLED NMKPTSSFEE
TSVTSAEVKP DIPLKKKHAN DLRGQAEQPR KISVSEADSD SSQSISDIPT ESESKPNIPD
KTRRRSRPKP ETVSEDERSR RHRPKPEVVT KDEEPRRRRP KPETTSEEEG SRRCRPKPET
VSEDEGSYPK APALPRKRPK RDSSTESLSS SVFLSSSSES LSSFETASLK ESSKSDSLPS
KTSSSVSEDA PEIPARKAKV KSLPIRQRKR ENSEDSSSAS AISKSSLKSC DLPPKEAMDL
CRKRTSIDER MIKLQNEGKC NTKEKAFIAA KLIEMQFEEE DALLASRQCN SVYHAVKFLT
QLCEMCNCRF PINLMASMVY CTHRACKECF KAHFTSLIYD RSVFTLLCPI CSKPDITDQN
IQEYFNHLDM LFRNILDSHV YDLFQRKLRD EVLTKDPNFH WCSQCSSGFI ASPRLKKLYC
PDCSAITCAL CHQTWELEHE GVHCERFQQW KDMHTPEPPP AGLVKYLADR GVTCPSCELV
YPQACGGCLM YKCSHCSFEF CGFCSRPYKR GKDCGNKSCE SRGIHCHHPY SCLFFLRDIE
MSDLQMLLEE ESVTYLTIPP KDQIVKSRCQ VREQKHIHGS FSEDRCGRDI VPYCAGLCRT
HYYEYLAELF RKKEINPLPI MTTRDLQFIL RKSRVLVPDR VKGETNDDYY KRLTEVISNT
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