ID A0A4Y3TZF9_9PROT Unreviewed; 431 AA.
AC A0A4Y3TZF9;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 28-JAN-2026, entry version 16.
DE RecName: Full=Arsenical pump membrane protein {ECO:0000256|RuleBase:RU004993};
GN ORFNames=APE01nite_22070 {ECO:0000313|EMBL:GEB86410.1};
OS Acetobacter peroxydans.
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Acetobacterales; Acetobacteraceae; Acetobacter.
OX NCBI_TaxID=104098 {ECO:0000313|EMBL:GEB86410.1, ECO:0000313|Proteomes:UP000317730};
RN [1] {ECO:0000313|EMBL:GEB86410.1, ECO:0000313|Proteomes:UP000317730}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 13755 {ECO:0000313|EMBL:GEB86410.1,
RC ECO:0000313|Proteomes:UP000317730};
RA Hosoyama A., Uohara A., Ohji S., Ichikawa N.;
RT "Whole genome shotgun sequence of Acetobacter peroxydans NBRC 13755.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in arsenical resistance. Thought to form the channel
CC of an arsenite pump. {ECO:0000256|RuleBase:RU004993}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC ECO:0000256|RuleBase:RU004993}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU004993}.
CC -!- SIMILARITY: Belongs to the ArsB family.
CC {ECO:0000256|RuleBase:RU004993}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU004993}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GEB86410.1}.
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DR EMBL; BJMV01000013; GEB86410.1; -; Genomic_DNA.
DR RefSeq; WP_141377529.1; NZ_BAPL01000022.1.
DR AlphaFoldDB; A0A4Y3TZF9; -.
DR OrthoDB; 9774335at2; -.
DR Proteomes; UP000317730; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0042960; F:antimonite secondary active transmembrane transporter activity; IEA:TreeGrafter.
DR GO; GO:0008490; F:arsenite secondary active transmembrane transporter activity; IEA:TreeGrafter.
DR GO; GO:0046685; P:response to arsenic-containing substance; IEA:UniProtKB-KW.
DR CDD; cd01118; ArsB_permease; 1.
DR InterPro; IPR000802; Arsenical_pump_ArsB.
DR NCBIfam; TIGR00935; 2a45; 1.
DR NCBIfam; NF011980; PRK15445.1; 1.
DR PANTHER; PTHR43302; TRANSPORTER ARSB-RELATED; 1.
DR PANTHER; PTHR43302:SF5; TRANSPORTER ARSB-RELATED; 1.
DR Pfam; PF02040; ArsB; 1.
DR PRINTS; PR00758; ARSENICPUMP.
PE 3: Inferred from homology;
KW Arsenical resistance {ECO:0000256|RuleBase:RU004993};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU004993};
KW Reference proteome {ECO:0000313|Proteomes:UP000317730};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU004993};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU004993}; Transport {ECO:0000256|RuleBase:RU004993}.
FT TRANSMEM 47..69
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004993"
FT TRANSMEM 90..108
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004993"
FT TRANSMEM 114..130
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004993"
FT TRANSMEM 135..155
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004993"
FT TRANSMEM 175..197
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004993"
FT TRANSMEM 221..238
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004993"
FT TRANSMEM 244..265
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004993"
FT TRANSMEM 277..295
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004993"
FT TRANSMEM 307..330
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004993"
FT TRANSMEM 402..425
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004993"
SQ SEQUENCE 431 AA; 46221 MW; D0DAD741E2113537 CRC64;
MLALALFILT LVFVIWQPRG LGIGWSALAG AGVALATGVI HWQDIPVVWH IVWDATFTFI
ALIIISLLLD EAGFFHWAAL HVVRWGRGRG RVLFPLIVLL GAAIAAIFAN DGAALLLTPI
VIAILAQLRL SQTAALAFII ATGFVADTTS LPLVISNLVN IVSANFFGIP FDRYAAIMVP
VDLVALGATL AALWAYFGRE IPTTYPVDTL PAPATAIRDR YVFRAAFPLL ALILLAYLLT
APLHIPVCVV AGLAASILLL VAGFGRVIPV RKVLRGAPWQ IVIFSLGMYL VVYGLRNAGL
TDYLASALVW LGHQGLFTAT IGTGFLAAVL SSIMNNMPSV LVGALAIQQT HDITPLTRDL
MVYANVIGCD LGPKFTPIGS LATLLWLHVL ASKNHRVTWG QYIKVGLIIT PPVLLVTLIA
LALWLPQISH P
//
