ID A0A4Y7TZ90_COPMI Unreviewed; 730 AA.
AC A0A4Y7TZ90;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 18-JUN-2025, entry version 19.
DE RecName: Full=Homeobox domain-containing protein {ECO:0000259|PROSITE:PS50071};
GN ORFNames=FA13DRAFT_1704553 {ECO:0000313|EMBL:TEB38899.1};
OS Coprinellus micaceus (Glistening ink-cap mushroom) (Coprinus micaceus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Psathyrellaceae; Coprinellus.
OX NCBI_TaxID=71717 {ECO:0000313|EMBL:TEB38899.1, ECO:0000313|Proteomes:UP000298030};
RN [1] {ECO:0000313|EMBL:TEB38899.1, ECO:0000313|Proteomes:UP000298030}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FP101781 {ECO:0000313|EMBL:TEB38899.1,
RC ECO:0000313|Proteomes:UP000298030};
RX PubMed=30886374; DOI=.1038/s41559-019-0834-1;
RA Varga T., Krizsan K., Foldi C., Dima B., Sanchez-Garcia M.,
RA Sanchez-Ramirez S., Szollosi G.J., Szarkandi J.G., Papp V., Albert L.,
RA Andreopoulos W., Angelini C., Antonin V., Barry K.W., Bougher N.L.,
RA Buchanan P., Buyck B., Bense V., Catcheside P., Chovatia M., Cooper J.,
RA Damon W., Desjardin D., Finy P., Geml J., Haridas S., Hughes K., Justo A.,
RA Karasinski D., Kautmanova I., Kiss B., Kocsube S., Kotiranta H.,
RA LaButti K.M., Lechner B.E., Liimatainen K., Lipzen A., Lukacs Z.,
RA Mihaltcheva S., Morgado L.N., Niskanen T., Noordeloos M.E., Ohm R.A.,
RA Ortiz-Santana B., Ovrebo C., Racz N., Riley R., Savchenko A., Shiryaev A.,
RA Soop K., Spirin V., Szebenyi C., Tomsovsky M., Tulloss R.E., Uehling J.,
RA Grigoriev I.V., Vagvolgyi C., Papp T., Martin F.M., Miettinen O.,
RA Hibbett D.S., Nagy L.G.;
RT "Megaphylogeny resolves global patterns of mushroom evolution.";
RL Nat. Ecol. Evol. 3:668-678(2019).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- SIMILARITY: Belongs to the TALE/M-ATYP homeobox family.
CC {ECO:0000256|ARBA:ARBA00005800}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TEB38899.1}.
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DR EMBL; QPFP01000002; TEB38899.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4Y7TZ90; -.
DR STRING; 71717.A0A4Y7TZ90; -.
DR OrthoDB; 250329at2759; -.
DR Proteomes; UP000298030; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR001356; HD.
DR InterPro; IPR009057; Homeodomain-like_sf.
DR InterPro; IPR024441; Homeodomain1_C.
DR InterPro; IPR008422; KN_HD.
DR InterPro; IPR024333; Mating-type_A-alpha/beta_1_N.
DR Pfam; PF05920; Homeobox_KN; 1.
DR Pfam; PF12737; Mating_C; 1.
DR Pfam; PF12731; Mating_N; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000298030}.
FT DOMAIN 278..314
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 280..315
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 391..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 442..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 678..698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..413
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..698
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 79868 MW; 9994CB48506615F4 CRC64;
MWACRYGADR PRSLRKSVKS GGTVKSSGGN SRFCVGSSIW DVESEALQGR WTRARQVWET
SRSRFKISRY VDDMAGFARE GRAAVLHLEG RTWANVYWKC SIGDWESVWK ASNLTLSVNP
LVALFKPINE GFTYPHGPPP SIFVMASRLP SLANKNYNSF ALSTLEELET QFFAALEDDA
IDSLFQFHSS WEQFQSQLEI VHLHLTPDTI ESITKFASVM VTVSQSMADS TPFDAVERFK
ANLNVELTTS IRDASAAPLP VRGYISASLR WLKTNIHNPY PSRETRRSIA KSTSTAVKDV
DAWFVDIRKR IGWSQLRHSR FSNRKAGIVD AATRFFNGSD PHRPLASIVE SEFASIAATV
DQLYYEKCAD STLASHLDES VRDFTPDLRQ SLSQGKQKAH LMARRSKSSR HRLNPYPTPE
LSPTLPFKSL CTTGPPLLAS SIASSSEKCR KRSRSPSSEC PTDIEGEIRS AKRTRTPTQA
PVSLEVEPTG HTGKRKSTLS DTGIVRAPPP RESDSQPRTS SDPPPLSVSE ILDQAAFCPP
SPSAVPSATS CAFGPFDPFF SAFMNGGAPA LGDTSSPLSL NIVDDVAPTN VHVEFDQSWL
SSSADALVPS YDPYATSYNT NFDNFGGNLY GGSVEPFSSP LWYGDPPSQS LVSAPCSEGS
TLTLTGQLNV SLPSQVDLHG VAPPSSHSPN YTPHSDPQTN KARELLELEA RCATLRSELA
AGRSGVSILP
//
